Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index
Parabens have been accepted almost worldwide as preservatives by the cosmetic, food, and pharmaceutical industries. Since epidemiological evidence of the obesogenic activity of parabens is weak, the aim of this study was to investigate the association between parabens exposure and childhood obesity....
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/5/1154 |
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| author | Inmaculada Moscoso-Ruiz Yolanda Gálvez-Ontiveros Cristina Samaniego-Sánchez Vega Almazán Fernández de Bobadilla Celia Monteagudo Alberto Zafra-Gómez Ana Rivas |
| author_facet | Inmaculada Moscoso-Ruiz Yolanda Gálvez-Ontiveros Cristina Samaniego-Sánchez Vega Almazán Fernández de Bobadilla Celia Monteagudo Alberto Zafra-Gómez Ana Rivas |
| author_sort | Inmaculada Moscoso-Ruiz |
| collection | DOAJ |
| description | Parabens have been accepted almost worldwide as preservatives by the cosmetic, food, and pharmaceutical industries. Since epidemiological evidence of the obesogenic activity of parabens is weak, the aim of this study was to investigate the association between parabens exposure and childhood obesity. Four parabens (methylparaben/MetPB, ethylparaben/EthPB, propylparaben/PropPB, and butylparaben/ButPB) were measured in 160 children’s bodies between 6 and 12 years of age. Parabens measurements were performed with ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). Logistic regression was used to evaluate risk factors for elevated body weight associated with paraben exposure. No significant relation was detected between children’s body weight and the presence of parabens in the samples. This study confirmed the omnipresence of parabens in children’s bodies. Our results could be a basis for future research about the effect of parabens on childhood body weight using nails as a biomarker due to the ease of its collection and its non-invasive character. |
| first_indexed | 2024-03-11T07:14:50Z |
| format | Article |
| id | doaj.art-b07a9136e3cf411aa328b71c4683751a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T07:14:50Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-b07a9136e3cf411aa328b71c4683751a2023-11-17T08:20:20ZengMDPI AGNutrients2072-66432023-02-01155115410.3390/nu15051154Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass IndexInmaculada Moscoso-Ruiz0Yolanda Gálvez-Ontiveros1Cristina Samaniego-Sánchez2Vega Almazán Fernández de Bobadilla3Celia Monteagudo4Alberto Zafra-Gómez5Ana Rivas6Department of Analytical Chemistry, University of Granada, 18071 Granada, SpainDepartment of Nutrition and Food Science, University of Granada, 18071 Granada, SpainDepartment of Nutrition and Food Science, University of Granada, 18071 Granada, SpainMaracena Healthcare Centre, Camino de los Eriales s/n, 18200 Granada, SpainDepartment of Nutrition and Food Science, University of Granada, 18071 Granada, SpainDepartment of Analytical Chemistry, University of Granada, 18071 Granada, SpainDepartment of Nutrition and Food Science, University of Granada, 18071 Granada, SpainParabens have been accepted almost worldwide as preservatives by the cosmetic, food, and pharmaceutical industries. Since epidemiological evidence of the obesogenic activity of parabens is weak, the aim of this study was to investigate the association between parabens exposure and childhood obesity. Four parabens (methylparaben/MetPB, ethylparaben/EthPB, propylparaben/PropPB, and butylparaben/ButPB) were measured in 160 children’s bodies between 6 and 12 years of age. Parabens measurements were performed with ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). Logistic regression was used to evaluate risk factors for elevated body weight associated with paraben exposure. No significant relation was detected between children’s body weight and the presence of parabens in the samples. This study confirmed the omnipresence of parabens in children’s bodies. Our results could be a basis for future research about the effect of parabens on childhood body weight using nails as a biomarker due to the ease of its collection and its non-invasive character.https://www.mdpi.com/2072-6643/15/5/1154parabensobesogenschildrenurinenailsaliva |
| spellingShingle | Inmaculada Moscoso-Ruiz Yolanda Gálvez-Ontiveros Cristina Samaniego-Sánchez Vega Almazán Fernández de Bobadilla Celia Monteagudo Alberto Zafra-Gómez Ana Rivas Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index Nutrients parabens obesogens children urine nail saliva |
| title | Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index |
| title_full | Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index |
| title_fullStr | Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index |
| title_full_unstemmed | Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index |
| title_short | Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index |
| title_sort | presence of parabens in different children biological matrices and its relationship with body mass index |
| topic | parabens obesogens children urine nail saliva |
| url | https://www.mdpi.com/2072-6643/15/5/1154 |
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