Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review
Case reportWe present a case of a 48-year-old woman with 27 months of exposure to aluminum dust and silica owing to polishing processing. The patient was admitted to our hospital with intermittent cough and expectoration. Chest high-resolution computed tomography showed diffuse ill-defined centrilob...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1085716/full |
| _version_ | 1811164138741694464 |
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| author | Xuqin Du Xuqin Du Lihong Song Ruie Feng Qiao Ye Qiao Ye |
| author_facet | Xuqin Du Xuqin Du Lihong Song Ruie Feng Qiao Ye Qiao Ye |
| author_sort | Xuqin Du |
| collection | DOAJ |
| description | Case reportWe present a case of a 48-year-old woman with 27 months of exposure to aluminum dust and silica owing to polishing processing. The patient was admitted to our hospital with intermittent cough and expectoration. Chest high-resolution computed tomography showed diffuse ill-defined centrilobular nodules and patchy ground-glass opacities in bilateral lungs. A video-assisted thoracoscopic surgery biopsy demonstrated multiple isolated and confluent granulomas in an otherwise normal parenchyma without malignancy or signs of infection. Elemental analysis was performed on the grinding wheel powder in the workplace using an X-ray fluorescence spectrometric analyzer, showing 72.7% of Al2O3 and 22.8% of SiO2 as raw materials. She was diagnosed with aluminum-associated sarcoid-like granulomatous lung disease, rather than sarcoidosis, according to occupational exposure by a multidisciplinary panel.ConclusionOccupational aluminum dust exposure may induce pulmonary sarcoid-like granulomatosis recognized by a multidisciplinary diagnostic panel. |
| first_indexed | 2024-04-10T15:17:30Z |
| format | Article |
| id | doaj.art-b07f796cc92c4b138640398e9ecd320e |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T15:17:30Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-b07f796cc92c4b138640398e9ecd320e2023-02-14T19:10:15ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-02-011010.3389/fmed.2023.10857161085716Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature reviewXuqin Du0Xuqin Du1Lihong Song2Ruie Feng3Qiao Ye4Qiao Ye5Department of Occupational Medicine and Toxicology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, ChinaClinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing, ChinaDepartment of Occupational Diseases, The Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai, ChinaDepartment of Pathology, Peking Union Medical College Hospital (CAMS), Beijing, ChinaDepartment of Occupational Medicine and Toxicology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, ChinaClinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing, ChinaCase reportWe present a case of a 48-year-old woman with 27 months of exposure to aluminum dust and silica owing to polishing processing. The patient was admitted to our hospital with intermittent cough and expectoration. Chest high-resolution computed tomography showed diffuse ill-defined centrilobular nodules and patchy ground-glass opacities in bilateral lungs. A video-assisted thoracoscopic surgery biopsy demonstrated multiple isolated and confluent granulomas in an otherwise normal parenchyma without malignancy or signs of infection. Elemental analysis was performed on the grinding wheel powder in the workplace using an X-ray fluorescence spectrometric analyzer, showing 72.7% of Al2O3 and 22.8% of SiO2 as raw materials. She was diagnosed with aluminum-associated sarcoid-like granulomatous lung disease, rather than sarcoidosis, according to occupational exposure by a multidisciplinary panel.ConclusionOccupational aluminum dust exposure may induce pulmonary sarcoid-like granulomatosis recognized by a multidisciplinary diagnostic panel.https://www.frontiersin.org/articles/10.3389/fmed.2023.1085716/fullgranulomatosissarcoidosislung diseasecase reportaluminum dust |
| spellingShingle | Xuqin Du Xuqin Du Lihong Song Ruie Feng Qiao Ye Qiao Ye Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review Frontiers in Medicine granulomatosis sarcoidosis lung disease case report aluminum dust |
| title | Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review |
| title_full | Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review |
| title_fullStr | Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review |
| title_full_unstemmed | Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review |
| title_short | Pulmonary sarcoid-like granulomatosis induced by aluminum dust: A case report and literature review |
| title_sort | pulmonary sarcoid like granulomatosis induced by aluminum dust a case report and literature review |
| topic | granulomatosis sarcoidosis lung disease case report aluminum dust |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1085716/full |
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