Five Constituents in Psoralea corylifolia L. Attenuate Palmitic Acid-Induced Hepatocyte Injury via Inhibiting the Protein Kinase C-α/Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Pathway

Five Constituents in Psoralea corylifolia L. Attenuate Palmitic Acid-Induced Hepatocyte Injury via Inhibiting the Protein Kinase C-α/Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Pathway

Psoralea corylifolia L. (PC) is a traditional Chinese herb used to treat yang deficiency of the spleen and kidney in pediatric disease. Our previous studies have found that PC can alleviate the liver oxidative stress of juvenile mice with nonalcoholic steatohepatitis (NASH), and its mechanism is rel...

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Bibliographic Details
Main Authors: Lishan Zhou, Jianqiao Tang, Xuan Yang, Hui Dong, Xiaoli Xiong, Juan Huang, Linli Zhang, Huan Qin, Suqi Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
Psoralea corylifolia L.
compounds
primary hepatocytes
nonalcoholic fatty liver disease
protein kinase C-α/nicotinamide-adenine dinucleotide phosphate oxidase signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01589/full

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