From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy

From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy

(1) Background: Mild hyperthermia (mHT, 39–42 °C) is a potent cancer treatment modality when delivered in conjunction with radiotherapy. mHT triggers a series of therapeutically relevant biological mechanisms, e.g., it can act as a radiosensitizer by improving tumor oxygenation, the latter generally...

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Bibliographic Details
Main Authors: Peter Vaupel, Helmut Piazena, Markus Notter, Andreas R. Thomsen, Anca-L. Grosu, Felix Scholkmann, Alan Graham Pockley, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
radio-oncology
mild hyperthermia
immuno-oncology
enhanced tumor blood flow
improved tumor oxygenation
physiological responses
Online Access:https://www.mdpi.com/2072-6694/15/5/1394

Internet

https://www.mdpi.com/2072-6694/15/5/1394

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