Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?

Klebsiella pneumoniae is a gram-negative pathogen that is a common cause of severe infections, including pyogenic liver abscess. Dissemination of K. pneumoniae to other organs, including the eye, is associated with significant morbidity and mortality. In the particular case of endogenous endophthalm...

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Main Authors: Catarina Correia, Sandra Lopes, Sofia Mendes, Nuno Almeida, Pedro Figueiredo
Format: Article
Language:English
Published: Karger Publishers 2021-09-01
Series:GE: Portuguese Journal of Gastroenterology
Subjects:
Online Access:https://www.karger.com/Article/FullText/518587
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author Catarina Correia
Sandra Lopes
Sofia Mendes
Nuno Almeida
Pedro Figueiredo
author_facet Catarina Correia
Sandra Lopes
Sofia Mendes
Nuno Almeida
Pedro Figueiredo
author_sort Catarina Correia
collection DOAJ
description Klebsiella pneumoniae is a gram-negative pathogen that is a common cause of severe infections, including pyogenic liver abscess. Dissemination of K. pneumoniae to other organs, including the eye, is associated with significant morbidity and mortality. In the particular case of endogenous endophthalmitis (EE) by K. pneumoniae the prognosis is poor. We report the case of a middle-aged female with K. pneumoniae liver abscess. The patient developed metastatic endophthalmitis that was aggressively treated with systemic antibiotics. The liver abscess resolved with antimicrobials and percutaneous transhepatic drainage, but regarding the endophthalmitis she was discharged from our hospital without recovery of her eyesight. Metastatic spread to the eye should be considered in all patients with liver abscesses who experience ocular signs and symptoms in order to establish a timely diagnosis of EE.
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spelling doaj.art-b0870fe1f21541a887e0bb0f674ea9c42022-12-21T19:07:19ZengKarger PublishersGE: Portuguese Journal of Gastroenterology2341-45452387-19542021-09-011610.1159/000518587518587Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?Catarina Correia0https://orcid.org/0000-0001-5609-5262Sandra Lopes1Sofia Mendes2Nuno Almeida3Pedro Figueiredo4Gastroenterology Department, Coimbra University Hospital Center, Coimbra, PortugalGastroenterology Department, Coimbra University Hospital Center, Coimbra, PortugalGastroenterology Department, Coimbra University Hospital Center, Coimbra, PortugalGastroenterology Department, Coimbra University Hospital Center, Coimbra, PortugalGastroenterology Department, Coimbra University Hospital Center, Coimbra, PortugalKlebsiella pneumoniae is a gram-negative pathogen that is a common cause of severe infections, including pyogenic liver abscess. Dissemination of K. pneumoniae to other organs, including the eye, is associated with significant morbidity and mortality. In the particular case of endogenous endophthalmitis (EE) by K. pneumoniae the prognosis is poor. We report the case of a middle-aged female with K. pneumoniae liver abscess. The patient developed metastatic endophthalmitis that was aggressively treated with systemic antibiotics. The liver abscess resolved with antimicrobials and percutaneous transhepatic drainage, but regarding the endophthalmitis she was discharged from our hospital without recovery of her eyesight. Metastatic spread to the eye should be considered in all patients with liver abscesses who experience ocular signs and symptoms in order to establish a timely diagnosis of EE.https://www.karger.com/Article/FullText/518587endogenous endophthalmitispyogenic liver abscesspercutaneous drainageklebsiella pneumoniae
spellingShingle Catarina Correia
Sandra Lopes
Sofia Mendes
Nuno Almeida
Pedro Figueiredo
Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
GE: Portuguese Journal of Gastroenterology
endogenous endophthalmitis
pyogenic liver abscess
percutaneous drainage
klebsiella pneumoniae
title Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
title_full Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
title_fullStr Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
title_full_unstemmed Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
title_short Endogenous Endophthalmitis and Liver Abscess: A Metastatic Infection or a Coincidence?
title_sort endogenous endophthalmitis and liver abscess a metastatic infection or a coincidence
topic endogenous endophthalmitis
pyogenic liver abscess
percutaneous drainage
klebsiella pneumoniae
url https://www.karger.com/Article/FullText/518587
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AT sandralopes endogenousendophthalmitisandliverabscessametastaticinfectionoracoincidence
AT sofiamendes endogenousendophthalmitisandliverabscessametastaticinfectionoracoincidence
AT nunoalmeida endogenousendophthalmitisandliverabscessametastaticinfectionoracoincidence
AT pedrofigueiredo endogenousendophthalmitisandliverabscessametastaticinfectionoracoincidence