Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy
Background: Significant left ventricular dysfunction may arise in right-sided accessory pathways with ventricular preexcitation in the absence of recurrent or incessant tachycardia. This has just been realized and not enough attention has been paid to it. Methods : In the last 7 years, we identifie...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Compuscript Ltd
2020-08-01
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| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0575 |
| _version_ | 1797793535324323840 |
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| author | Chencheng Dai Baojing Guo Ling Han Caihua Sang Jianzeng Dong Changsheng Ma |
| author_facet | Chencheng Dai Baojing Guo Ling Han Caihua Sang Jianzeng Dong Changsheng Ma |
| author_sort | Chencheng Dai |
| collection | DOAJ |
| description | Background: Significant left ventricular dysfunction may arise in right-sided accessory pathways with ventricular preexcitation in the absence of recurrent or incessant tachycardia. This has just been realized and not enough attention has been paid to it. Methods : In the last 7 years, we identified 12 consecutive children with a diagnosis of ventricular preexcitation–induced dilated cardiomyopathy. This report describes the clinical and echocardiographic characteristics of the patients before and after ablation. Results: Dyssynchronous ventricular contraction was observed by M-mode echocardiography and two-dimensional strain analysis in all patients. The basal and middle segments of the interventricular septum became thin and moved similarly to an aneurysm, with typical bulging during the end of systole. The locations of the accessory pathways were the right-sided septum ( n =5) and the free wall ( n =7). Left ventricular synchrony was obtained shortly after ablation. The left ventricular function recovered to normal and the left ventricular end-diastolic diameter decreased gradually during follow-up. Conclusions: A causal relationship between ventricular preexcitation and the development of dilated cardiomyopathy is supported by the complete recovery of left ventricular function and reversed left ventricular remodeling after the loss of ventricular preexcitation. Preexcitation-related dyssynchrony was thought to be the crucial mechanism. Ventricular preexcitation–induced dilated cardiomyopathy is an indication for ablation with a good prognosis. |
| first_indexed | 2024-03-13T02:48:45Z |
| format | Article |
| id | doaj.art-b08c43021a70469cad13bcbc155b3515 |
| institution | Directory Open Access Journal |
| issn | 2009-8618 2009-8782 |
| language | English |
| last_indexed | 2024-03-13T02:48:45Z |
| publishDate | 2020-08-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Cardiovascular Innovations and Applications |
| spelling | doaj.art-b08c43021a70469cad13bcbc155b35152023-06-28T14:10:06ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822020-08-0151910.15212/CVIA.2019.0575Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated CardiomyopathyChencheng DaiBaojing GuoLing HanCaihua SangJianzeng DongChangsheng MaBackground: Significant left ventricular dysfunction may arise in right-sided accessory pathways with ventricular preexcitation in the absence of recurrent or incessant tachycardia. This has just been realized and not enough attention has been paid to it. Methods : In the last 7 years, we identified 12 consecutive children with a diagnosis of ventricular preexcitation–induced dilated cardiomyopathy. This report describes the clinical and echocardiographic characteristics of the patients before and after ablation. Results: Dyssynchronous ventricular contraction was observed by M-mode echocardiography and two-dimensional strain analysis in all patients. The basal and middle segments of the interventricular septum became thin and moved similarly to an aneurysm, with typical bulging during the end of systole. The locations of the accessory pathways were the right-sided septum ( n =5) and the free wall ( n =7). Left ventricular synchrony was obtained shortly after ablation. The left ventricular function recovered to normal and the left ventricular end-diastolic diameter decreased gradually during follow-up. Conclusions: A causal relationship between ventricular preexcitation and the development of dilated cardiomyopathy is supported by the complete recovery of left ventricular function and reversed left ventricular remodeling after the loss of ventricular preexcitation. Preexcitation-related dyssynchrony was thought to be the crucial mechanism. Ventricular preexcitation–induced dilated cardiomyopathy is an indication for ablation with a good prognosis.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0575 |
| spellingShingle | Chencheng Dai Baojing Guo Ling Han Caihua Sang Jianzeng Dong Changsheng Ma Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy Cardiovascular Innovations and Applications |
| title | Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy |
| title_full | Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy |
| title_fullStr | Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy |
| title_full_unstemmed | Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy |
| title_short | Dyssynchrony Induced by Ventricular Preexcitation: A Risk Factor for the Development of Dilated Cardiomyopathy |
| title_sort | dyssynchrony induced by ventricular preexcitation a risk factor for the development of dilated cardiomyopathy |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0575 |
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