Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial

Sinus augmentation procedures have become a valuable solution for patients with posterior maxillary edentulism. The objective of this study was to explore the efficacy and safety of porcine xenograft with collagen supplementation as a potential alternative to autologous bone grafts in lateral sinus...

Full description

Bibliographic Details
Main Authors: Francisco Correia, Sónia Gouveia, António Campos Felino, Ricardo Faria-Almeida, Daniel H. Pozza
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Dentistry Journal
Subjects:
Online Access:https://www.mdpi.com/2304-6767/12/2/33
_version_ 1797298504693972992
author Francisco Correia
Sónia Gouveia
António Campos Felino
Ricardo Faria-Almeida
Daniel H. Pozza
author_facet Francisco Correia
Sónia Gouveia
António Campos Felino
Ricardo Faria-Almeida
Daniel H. Pozza
author_sort Francisco Correia
collection DOAJ
description Sinus augmentation procedures have become a valuable solution for patients with posterior maxillary edentulism. The objective of this study was to explore the efficacy and safety of porcine xenograft with collagen supplementation as a potential alternative to autologous bone grafts in lateral sinus augmentation over a three-year follow-up period. Twelve patients, each with bilateral posterior maxillary edentulism, were enrolled and randomly allocated to receive either a porcine xenograft or an autologous graft. Comprehensive assessments, including clinical and radiographic evaluations, were conducted at specific intervals, including implant stability, marginal bone loss, prosthetic and biological complications, and patient preferences. The results demonstrated no significant differences between the two graft materials in terms of implant survival, marginal bone loss, and patient preferences after three years of follow-up. Only one implant was affected by peri-implantitis, and prosthesis-related complications were present in one patient possibly due to bruxism. In conclusion, these findings suggest that a porcine xenograft with collagen supplementation may be a viable alternative to an autograft in lateral sinus augmentation procedures. The high implant survival rate, minimal complications, and patient satisfaction indicate the potential clinical relevance of this graft material and should be further investigated to confirm these promising results.
first_indexed 2024-03-07T22:35:46Z
format Article
id doaj.art-b0908bce39ee4378bfe50f6cd22b2571
institution Directory Open Access Journal
issn 2304-6767
language English
last_indexed 2024-03-07T22:35:46Z
publishDate 2024-02-01
publisher MDPI AG
record_format Article
series Dentistry Journal
spelling doaj.art-b0908bce39ee4378bfe50f6cd22b25712024-02-23T15:13:34ZengMDPI AGDentistry Journal2304-67672024-02-011223310.3390/dj12020033Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled TrialFrancisco Correia0Sónia Gouveia1António Campos Felino2Ricardo Faria-Almeida3Daniel H. Pozza4Specialization in Periodontology and Implants, Faculty of Dental Medicine, University of Porto, 4200-393 Porto, PortugalDepartment of Electronics, Telecommunications and Informatics (DETI), Institute of Electronics and Informatics Engineering of Aveiro (IEETA), University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Oral Surgery and Periodontology, Faculty of Dental Medicine, University of Porto, 4200-393 Porto, PortugalSpecialization in Periodontology and Implants, Faculty of Dental Medicine, University of Porto, 4200-393 Porto, PortugalExperimental Biology Unit, Department of Biomedicine, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, PortugalSinus augmentation procedures have become a valuable solution for patients with posterior maxillary edentulism. The objective of this study was to explore the efficacy and safety of porcine xenograft with collagen supplementation as a potential alternative to autologous bone grafts in lateral sinus augmentation over a three-year follow-up period. Twelve patients, each with bilateral posterior maxillary edentulism, were enrolled and randomly allocated to receive either a porcine xenograft or an autologous graft. Comprehensive assessments, including clinical and radiographic evaluations, were conducted at specific intervals, including implant stability, marginal bone loss, prosthetic and biological complications, and patient preferences. The results demonstrated no significant differences between the two graft materials in terms of implant survival, marginal bone loss, and patient preferences after three years of follow-up. Only one implant was affected by peri-implantitis, and prosthesis-related complications were present in one patient possibly due to bruxism. In conclusion, these findings suggest that a porcine xenograft with collagen supplementation may be a viable alternative to an autograft in lateral sinus augmentation procedures. The high implant survival rate, minimal complications, and patient satisfaction indicate the potential clinical relevance of this graft material and should be further investigated to confirm these promising results.https://www.mdpi.com/2304-6767/12/2/33sinus augmentationxenograftsbone transplantationdental implantsgraft survivalpatient preferences
spellingShingle Francisco Correia
Sónia Gouveia
António Campos Felino
Ricardo Faria-Almeida
Daniel H. Pozza
Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
Dentistry Journal
sinus augmentation
xenografts
bone transplantation
dental implants
graft survival
patient preferences
title Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
title_full Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
title_fullStr Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
title_full_unstemmed Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
title_short Maxillary Sinus Augmentation with Xenogenic Collagen-Retained Heterologous Cortico-Cancellous Bone: A 3-Year Follow-Up Randomized Controlled Trial
title_sort maxillary sinus augmentation with xenogenic collagen retained heterologous cortico cancellous bone a 3 year follow up randomized controlled trial
topic sinus augmentation
xenografts
bone transplantation
dental implants
graft survival
patient preferences
url https://www.mdpi.com/2304-6767/12/2/33
work_keys_str_mv AT franciscocorreia maxillarysinusaugmentationwithxenogeniccollagenretainedheterologouscorticocancellousbonea3yearfollowuprandomizedcontrolledtrial
AT soniagouveia maxillarysinusaugmentationwithxenogeniccollagenretainedheterologouscorticocancellousbonea3yearfollowuprandomizedcontrolledtrial
AT antoniocamposfelino maxillarysinusaugmentationwithxenogeniccollagenretainedheterologouscorticocancellousbonea3yearfollowuprandomizedcontrolledtrial
AT ricardofariaalmeida maxillarysinusaugmentationwithxenogeniccollagenretainedheterologouscorticocancellousbonea3yearfollowuprandomizedcontrolledtrial
AT danielhpozza maxillarysinusaugmentationwithxenogeniccollagenretainedheterologouscorticocancellousbonea3yearfollowuprandomizedcontrolledtrial