Insights on TAM Formation from a Boolean Model of Macrophage Polarization Based on In Vitro Studies

Insights on TAM Formation from a Boolean Model of Macrophage Polarization Based on In Vitro Studies

The tumour microenvironment is the surrounding of a tumour, including blood vessels, fibroblasts, signaling molecules, the extracellular matrix and immune cells, especially neutrophils and monocyte-derived macrophages. In a tumour setting, macrophages encompass a spectrum between a tumour-suppressiv...

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Bibliographic Details
Main Authors: Malvina Marku, Nina Verstraete, Flavien Raynal, Miguel Madrid-Mencía, Marcin Domagala, Jean-Jacques Fournié, Loïc Ysebaert, Mary Poupot, Vera Pancaldi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
Boolean model
tumour associated macrophage
macrophage polarization
nurse-like cells
chronic lymphocytic leukaemia
Online Access:https://www.mdpi.com/2072-6694/12/12/3664

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