C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients
Purpose: The aim of this retrospective observational study is to compare C-reactive protein to albumin ratio and CURB-65 score in the emergency department in terms of predicting mortality in patients over the age of 18 who were hospitalized for COVID-19 pneumonia. Materials and Methods: The study in...
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| Format: | Article |
| Language: | English |
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Cukurova University
2021-12-01
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| Series: | Cukurova Medical Journal |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1902093 |
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| author | Gonca Koksaldı Nurdan Unlu Selen Acehan Müge Gülen Cem Isikber Adem Kaya Cagdas Ince Basak Toptas Firat Hilmi Erdem Sümbül Salim Satar |
| author_facet | Gonca Koksaldı Nurdan Unlu Selen Acehan Müge Gülen Cem Isikber Adem Kaya Cagdas Ince Basak Toptas Firat Hilmi Erdem Sümbül Salim Satar |
| author_sort | Gonca Koksaldı |
| collection | DOAJ |
| description | Purpose: The aim of this retrospective observational study is to compare C-reactive protein to albumin ratio and CURB-65 score in the emergency department in terms of predicting mortality in patients over the age of 18 who were hospitalized for COVID-19 pneumonia.
Materials and Methods: The study includes 613 patients hospitalized between March 15 and April 30, 2020 due to COVID-19 pneumonia detected on thorax computed tomography at the emergency department pandemic area. Hospitalized patients were divided into groups according to positive and negative real-time polymerase chain reaction results.
Results: While 73.1% (n: 448) of 613 patients included in the study were hospitalized in the ward, 26.9% (n: 165) were hospitalized in intensive care. 8.6% (n: 53) of the total patients died. In non-survivors patients the mean CURB 65 score was 4±1 (and C-Reactive Protein to Albumin Ratio was 5.6±4.2 Multivariate logistic regression analysis showed that CURB 65 and high C-Reactive Protein to Albumin Ratio are independent risk factors for COVID-19 pneumonia.
Conclusion: The C-reactive protein to albumin ratio is as sensitive as CURB 65 and can guide the clinician in the early detection of patients with poor prognosis COVID-19 pneumonia. |
| first_indexed | 2024-04-10T14:02:25Z |
| format | Article |
| id | doaj.art-b0934b0c54f34a5daa43b6759797b01d |
| institution | Directory Open Access Journal |
| issn | 2602-3040 |
| language | English |
| last_indexed | 2024-04-10T14:02:25Z |
| publishDate | 2021-12-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Cukurova Medical Journal |
| spelling | doaj.art-b0934b0c54f34a5daa43b6759797b01d2023-02-15T16:10:13ZengCukurova UniversityCukurova Medical Journal2602-30402021-12-014641449145810.17826/cumj.97705048C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patientsGonca Koksaldı0Nurdan Unlu1Selen Acehan2Müge Gülen3Cem Isikber4Adem Kaya5Cagdas Ince6Basak Toptas Firat7Hilmi Erdem Sümbül8Salim Satar9Adana City Training and Research Hospital, Department of Emergency Medicine,Adana City Training and Research Hospital, Department of Anesthesiology and Intensive CareAdana City Training and Research Hospital, Department of Emergency Medicine,Adana City Training and Research Hospital, Department of Emergency MedicineAdana City Training and Research Hospital, Department of Emergency MedicineAdana City Training and Research Hospital, Department of Emergency MedicineAdana City Training and Research Hospital, Department of Emergency MedicineAdana City Training and Research Hospital, Department of Emergency MedicineAdana City Training and Research Hospital, Department of İnternal MedicineAdana City Training and Research Hospital, Department of Emergency MedicinePurpose: The aim of this retrospective observational study is to compare C-reactive protein to albumin ratio and CURB-65 score in the emergency department in terms of predicting mortality in patients over the age of 18 who were hospitalized for COVID-19 pneumonia. Materials and Methods: The study includes 613 patients hospitalized between March 15 and April 30, 2020 due to COVID-19 pneumonia detected on thorax computed tomography at the emergency department pandemic area. Hospitalized patients were divided into groups according to positive and negative real-time polymerase chain reaction results. Results: While 73.1% (n: 448) of 613 patients included in the study were hospitalized in the ward, 26.9% (n: 165) were hospitalized in intensive care. 8.6% (n: 53) of the total patients died. In non-survivors patients the mean CURB 65 score was 4±1 (and C-Reactive Protein to Albumin Ratio was 5.6±4.2 Multivariate logistic regression analysis showed that CURB 65 and high C-Reactive Protein to Albumin Ratio are independent risk factors for COVID-19 pneumonia. Conclusion: The C-reactive protein to albumin ratio is as sensitive as CURB 65 and can guide the clinician in the early detection of patients with poor prognosis COVID-19 pneumonia.https://dergipark.org.tr/tr/download/article-file/1902093crp/albumine ratiocovid-19curb 65emergency departmentpneumoniaacil serviscrp/albümin oranıcovid-19curb 65pnömoni |
| spellingShingle | Gonca Koksaldı Nurdan Unlu Selen Acehan Müge Gülen Cem Isikber Adem Kaya Cagdas Ince Basak Toptas Firat Hilmi Erdem Sümbül Salim Satar C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients Cukurova Medical Journal crp/albumine ratio covid-19 curb 65 emergency department pneumonia acil servis crp/albümin oranı covid-19 curb 65 pnömoni |
| title | C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients |
| title_full | C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients |
| title_fullStr | C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients |
| title_full_unstemmed | C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients |
| title_short | C-reactive protein to albumin ratio is associated with increased risk of mortality in COVID-19 pneumonia patients |
| title_sort | c reactive protein to albumin ratio is associated with increased risk of mortality in covid 19 pneumonia patients |
| topic | crp/albumine ratio covid-19 curb 65 emergency department pneumonia acil servis crp/albümin oranı covid-19 curb 65 pnömoni |
| url | https://dergipark.org.tr/tr/download/article-file/1902093 |
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