The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation.
Histone H3 and its variants regulate gene expression but the latter are absent in most ascomycetous fungi. Here, we report the identification of a variant histone H3, which we have designated H3VCTG because of its exclusive presence in the CTG clade of ascomycetes, including Candida albicans, a huma...
Main Authors: | Laxmi Shanker Rai, Rima Singha, Hiram Sanchez, Tanmoy Chakraborty, Bipin Chand, Sophie Bachellier-Bassi, Shantanu Chowdhury, Christophe d'Enfert, David R Andes, Kaustuv Sanyal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-08-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000422 |
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