Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States

Abstract Objective To examine opioid prescribing practices for pain in older adults with and without Alzheimer’s Disease and Related Dementias (ADRD). Methods This cross-sectional study used National Ambulatory Medical Care Survey data (2014–2016, and 2018). Adults aged ≥ 50 years with pain were ana...

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Main Authors: Yinan Huang, Rajender R Aparasu, Tyler J Varisco
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Geriatrics
Subjects:
Online Access:https://doi.org/10.1186/s12877-023-04115-6
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author Yinan Huang
Rajender R Aparasu
Tyler J Varisco
author_facet Yinan Huang
Rajender R Aparasu
Tyler J Varisco
author_sort Yinan Huang
collection DOAJ
description Abstract Objective To examine opioid prescribing practices for pain in older adults with and without Alzheimer’s Disease and Related Dementias (ADRD). Methods This cross-sectional study used National Ambulatory Medical Care Survey data (2014–2016, and 2018). Adults aged ≥ 50 years with pain were analyzed. Prescribing of opioid and concomitant sedative prescriptions (including benzodiazepines, Z-drugs, and barbiturates) were identified by the Multum lexicon code. Multivariable logistic regression evaluated the risk of opioid prescribing or co-prescribing of opioid and sedative associated with ADRD in older adults with pain. Results There were 13,299 office visits in older adults with pain, representing 451.75 million visits. Opioid prescribing occurred in 27.19%; 30% involved co-prescribing of opioids and sedatives. ADRD was not associated with opioid prescribing or co-prescribing of opioid and sedative therapy. Conclusions Opioid and sedatives are commonly prescribed in older adults with pain. Longitudinal studies need to understand the etiology and chronicity of opioid use in older patients, specifically with ADRD.
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spelling doaj.art-b095b6e9344f4b0384f4fa59a5faec012023-08-06T11:24:21ZengBMCBMC Geriatrics1471-23182023-08-012311610.1186/s12877-023-04115-6Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United StatesYinan Huang0Rajender R Aparasu1Tyler J Varisco2Department of Pharmacy Administration, University of Mississippi College of PharmacyDepartment of Pharmaceutical Health Outcome and Policy, University of Houston College of PharmacyDepartment of Pharmaceutical Health Outcome and Policy, University of Houston College of PharmacyAbstract Objective To examine opioid prescribing practices for pain in older adults with and without Alzheimer’s Disease and Related Dementias (ADRD). Methods This cross-sectional study used National Ambulatory Medical Care Survey data (2014–2016, and 2018). Adults aged ≥ 50 years with pain were analyzed. Prescribing of opioid and concomitant sedative prescriptions (including benzodiazepines, Z-drugs, and barbiturates) were identified by the Multum lexicon code. Multivariable logistic regression evaluated the risk of opioid prescribing or co-prescribing of opioid and sedative associated with ADRD in older adults with pain. Results There were 13,299 office visits in older adults with pain, representing 451.75 million visits. Opioid prescribing occurred in 27.19%; 30% involved co-prescribing of opioids and sedatives. ADRD was not associated with opioid prescribing or co-prescribing of opioid and sedative therapy. Conclusions Opioid and sedatives are commonly prescribed in older adults with pain. Longitudinal studies need to understand the etiology and chronicity of opioid use in older patients, specifically with ADRD.https://doi.org/10.1186/s12877-023-04115-6Opioid prescribingOlder adultsPain managementPrescribing patternAlzheimer’s diseases
spellingShingle Yinan Huang
Rajender R Aparasu
Tyler J Varisco
Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
BMC Geriatrics
Opioid prescribing
Older adults
Pain management
Prescribing pattern
Alzheimer’s diseases
title Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
title_full Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
title_fullStr Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
title_full_unstemmed Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
title_short Outpatient opioid prescribing by Alzheimer’s diagnosis among older adults with pain in United States
title_sort outpatient opioid prescribing by alzheimer s diagnosis among older adults with pain in united states
topic Opioid prescribing
Older adults
Pain management
Prescribing pattern
Alzheimer’s diseases
url https://doi.org/10.1186/s12877-023-04115-6
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AT rajenderraparasu outpatientopioidprescribingbyalzheimersdiagnosisamongolderadultswithpaininunitedstates
AT tylerjvarisco outpatientopioidprescribingbyalzheimersdiagnosisamongolderadultswithpaininunitedstates