Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece

<p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQoL) is an important outcome measure in Inflammatory Bowel Disease (IBD). The aim of our study was to assess HRQoL in a population of 135 Greek patients with IBD.</p> <p>Methods</p>...

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Main Authors: Mouzas Ioannis A, Vlachonikolis Ioannis G, Pallis Athanasios G
Format: Article
Language:English
Published: BMC 2002-01-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/2/1
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author Mouzas Ioannis A
Vlachonikolis Ioannis G
Pallis Athanasios G
author_facet Mouzas Ioannis A
Vlachonikolis Ioannis G
Pallis Athanasios G
author_sort Mouzas Ioannis A
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQoL) is an important outcome measure in Inflammatory Bowel Disease (IBD). The aim of our study was to assess HRQoL in a population of 135 Greek patients with IBD.</p> <p>Methods</p> <p>A cohort of 135 patients with IBD, 81 with ulcerative colitis (UC) and 54 with Crohn's disease (CD) were enrolled in our study. Demographic and disease-related data were recorded. HRQoL was assessed by a disease-specific and a generic questionnaire, IBDQ and SF-36, respectively. Disease activity was assessed by Harvey-Bradshaw Index and the Colitis Activity Index for CD and UC patients, respectively.</p> <p>Results</p> <p>Among all variables recorded in our study, only disease activity had a significant effect on HRQoL. Patients with active disease scored significantly lower on both IBDQ and SF-36 when compared to those in remission. Only two among the four IBDQ dimensions, bowel and systemic, had significant ability in distinguishing best patients in remission from those with active disease.</p> <p>Conclusions</p> <p>IBD has a negative impact on HRQoL. Patients with active disease are more impaired than patients in remission. In our population of patients bowel and systemic dimensions had a predominant value in patients' perception of quality of life. Patients in our study using the same instrument scored higher than previously reported.</p>
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spelling doaj.art-b0969234fefe4c889f460f1a28f1ffd32022-12-21T20:39:58ZengBMCBMC Gastroenterology1471-230X2002-01-0121110.1186/1471-230X-2-1Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, GreeceMouzas Ioannis AVlachonikolis Ioannis GPallis Athanasios G<p>Abstract</p> <p>Background</p> <p>Health Related Quality of Life (HRQoL) is an important outcome measure in Inflammatory Bowel Disease (IBD). The aim of our study was to assess HRQoL in a population of 135 Greek patients with IBD.</p> <p>Methods</p> <p>A cohort of 135 patients with IBD, 81 with ulcerative colitis (UC) and 54 with Crohn's disease (CD) were enrolled in our study. Demographic and disease-related data were recorded. HRQoL was assessed by a disease-specific and a generic questionnaire, IBDQ and SF-36, respectively. Disease activity was assessed by Harvey-Bradshaw Index and the Colitis Activity Index for CD and UC patients, respectively.</p> <p>Results</p> <p>Among all variables recorded in our study, only disease activity had a significant effect on HRQoL. Patients with active disease scored significantly lower on both IBDQ and SF-36 when compared to those in remission. Only two among the four IBDQ dimensions, bowel and systemic, had significant ability in distinguishing best patients in remission from those with active disease.</p> <p>Conclusions</p> <p>IBD has a negative impact on HRQoL. Patients with active disease are more impaired than patients in remission. In our population of patients bowel and systemic dimensions had a predominant value in patients' perception of quality of life. Patients in our study using the same instrument scored higher than previously reported.</p>http://www.biomedcentral.com/1471-230X/2/1
spellingShingle Mouzas Ioannis A
Vlachonikolis Ioannis G
Pallis Athanasios G
Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
BMC Gastroenterology
title Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
title_full Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
title_fullStr Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
title_full_unstemmed Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
title_short Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece
title_sort assessing health related quality of life in patients with inflammatory bowel disease in crete greece
url http://www.biomedcentral.com/1471-230X/2/1
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