Joint interpretation of AER/FGF and ZPA/SHH over time and space underlies hairy2 expression in the chick limb

Joint interpretation of AER/FGF and ZPA/SHH over time and space underlies hairy2 expression in the chick limb

Summary Embryo development requires precise orchestration of cell proliferation and differentiation in both time and space. A molecular clock operating through gene expression oscillations was first described in the presomitic mesoderm (PSM) underlying periodic somite formation. Cycles of HES gene e...

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Bibliographic Details
Main Authors: Caroline J. Sheeba, Raquel P. Andrade, Isabel Palmeirim
Format: Article
Language:English
Published: The Company of Biologists 2012-08-01
Series:Biology Open
Subjects:
Fibroblast growth factor
HES expression
Limb development
Sonic hedgehog
Online Access:http://bio.biologists.org/content/1/11/1102

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