Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

Mucociliary clearance (MCC), considered as a collaboration of mucus secreted from goblet cells, the airway surface liquid layer, and the beating of cilia of ciliated cells, is the airways’ defense system against airborne contaminants. Because the process is well described at the molecular level, we...

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Bibliographic Details
Main Authors: Hasmik Yepiskoposyan, Marja Talikka, Stefano Vavassori, Florian Martin, Alain Sewer, Sylvain Gubian, Karsta Luettich, Manuel Claude Peitsch, Julia Hoeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
mucociliary clearance
network models
biological expression language
respiratory tract
network perturbation amplitude
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00087/full

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