Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention

Autism Spectrum Disorder (ASD) disease has become a mounting socio-economical alarm around the world. Neuroinflammtion had been shown in postmortem brain specimens from ASD patients. The Endocannabinoids System (ES) consists of a family of locally produced, short-lived, endogenous, phospholipid-de...

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Main Authors: Syed Shahid Habib, Khalid Al-Regaiey, Shahid Bashir, Muhammad Iqbal
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/9969/c_CE[Ra]_F(Sh)_PF1(SG_SS)_PFA(SG_SS)_PF2(P_NE_AD).pdf
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author Syed Shahid Habib
Khalid Al-Regaiey
Shahid Bashir
Muhammad Iqbal
author_facet Syed Shahid Habib
Khalid Al-Regaiey
Shahid Bashir
Muhammad Iqbal
author_sort Syed Shahid Habib
collection DOAJ
description Autism Spectrum Disorder (ASD) disease has become a mounting socio-economical alarm around the world. Neuroinflammtion had been shown in postmortem brain specimens from ASD patients. The Endocannabinoids System (ES) consists of a family of locally produced, short-lived, endogenous, phospholipid-derived agonists (endocannabinoids) that control energy balance and body composition. The growing number of medical benefits of ES, such as their ability to regulate processes like neuroinflammation, neurogenesis and memory, raise the question of their potential role as a preventive treatment of ASD. To test this hypothesis, basic and clinical studies allow us a thorough investigation of the role of ES in the pathogenesis of ASD. This hypothesis will help to understand the mechanism of ES and its role in ASD.
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spelling doaj.art-b09edac2f0d8431baad4ca6acdc754f12022-12-22T00:23:30ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-06-01116CE01CE0310.7860/JCDR/2017/23862.9969Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder PreventionSyed Shahid Habib0Khalid Al-Regaiey1Shahid Bashir2Muhammad Iqbal3Professor, Department of Physiology, King Saud University, Riyadh, Saudi Arabia.Assistant Professor, Department of Physiology, King Saud University, Riyadh, Saudi Arabia.Assistant Professor, Department of Physiology, King Saud University, Riyadh, Saudi Arabia.Researcher, Department of Physiology, King Saud University, Riyadh, Saudi Arabia.Autism Spectrum Disorder (ASD) disease has become a mounting socio-economical alarm around the world. Neuroinflammtion had been shown in postmortem brain specimens from ASD patients. The Endocannabinoids System (ES) consists of a family of locally produced, short-lived, endogenous, phospholipid-derived agonists (endocannabinoids) that control energy balance and body composition. The growing number of medical benefits of ES, such as their ability to regulate processes like neuroinflammation, neurogenesis and memory, raise the question of their potential role as a preventive treatment of ASD. To test this hypothesis, basic and clinical studies allow us a thorough investigation of the role of ES in the pathogenesis of ASD. This hypothesis will help to understand the mechanism of ES and its role in ASD.https://jcdr.net/articles/PDF/9969/c_CE[Ra]_F(Sh)_PF1(SG_SS)_PFA(SG_SS)_PF2(P_NE_AD).pdfendocannabinoid systemneuroimmunomodulationneuroprotection
spellingShingle Syed Shahid Habib
Khalid Al-Regaiey
Shahid Bashir
Muhammad Iqbal
Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
Journal of Clinical and Diagnostic Research
endocannabinoid system
neuroimmunomodulation
neuroprotection
title Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
title_full Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
title_fullStr Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
title_full_unstemmed Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
title_short Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention
title_sort role of endocannabinoids on neuroinflammation in autism spectrum disorder prevention
topic endocannabinoid system
neuroimmunomodulation
neuroprotection
url https://jcdr.net/articles/PDF/9969/c_CE[Ra]_F(Sh)_PF1(SG_SS)_PFA(SG_SS)_PF2(P_NE_AD).pdf
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