THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY
The review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and En...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2019-04-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1252 |
| _version_ | 1797696702881202176 |
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| author | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina |
| author_facet | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina |
| author_sort | S. Yu. Degtyareva |
| collection | DOAJ |
| description | The review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and English databases. Most of the studies did not reveal a confident relation between the simultaneous use of antiretroviral and anti-tuberculosis therapy with second line drugs and increased frequency of adverse events. At the same time, in the largest studies, as well as studies devoted to certain adverse events, the authors managed to prove the existence of such a connection. Data on the structure of adverse events also significantly differed in the results obtained by various authors. Most trials were conducted in African countries with a high prevalence of HIV infection. |
| first_indexed | 2024-03-12T03:30:08Z |
| format | Article |
| id | doaj.art-b09edb558ffb4cf596ea8d19b11386aa |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T03:30:08Z |
| publishDate | 2019-04-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-b09edb558ffb4cf596ea8d19b11386aa2023-09-03T13:29:13ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-04-01973465310.21292/2075-1230-2019-97-3-46-531252THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPYS. Yu. Degtyareva0E. N. Beloborodova1A. V. Pokrovskaya2Yu. A. Klimova3I. B. Viktorova4V. N. Zimina5ФГАОУ ВО «Российский университет дружбы народов», г. МоскваФГАОУ ВО «Российский университет дружбы народов», г. МоскваФГАОУ ВО «Российский университет дружбы народов», г. Москва; ФБУН «Центральный НИИ эпидемиологии» Роспотребнадзора, г. МоскваФГАОУ ВО «Российский университет дружбы народов», г. МоскваНовокузнецкий государственный институт усовершенствования врачей ‒ филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» МЗ РФ, г. НовокузнецкФГАОУ ВО «Российский университет дружбы народов», г. МоскваThe review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and English databases. Most of the studies did not reveal a confident relation between the simultaneous use of antiretroviral and anti-tuberculosis therapy with second line drugs and increased frequency of adverse events. At the same time, in the largest studies, as well as studies devoted to certain adverse events, the authors managed to prove the existence of such a connection. Data on the structure of adverse events also significantly differed in the results obtained by various authors. Most trials were conducted in African countries with a high prevalence of HIV infection.https://www.tibl-journal.com/jour/article/view/1252антиретровирусная терапияпротивотуберкулезная терапиякоинфекция млу-тб/вич-инфекциянежелательные явления |
| spellingShingle | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY Туберкулез и болезни лёгких антиретровирусная терапия противотуберкулезная терапия коинфекция млу-тб/вич-инфекция нежелательные явления |
| title | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_full | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_fullStr | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_full_unstemmed | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_short | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_sort | safety of treatment of multiple drug resistant tuberculosis in hiv positive patients receiving antiretroviral therapy |
| topic | антиретровирусная терапия противотуберкулезная терапия коинфекция млу-тб/вич-инфекция нежелательные явления |
| url | https://www.tibl-journal.com/jour/article/view/1252 |
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