Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Εμφάνιση άλλων εκδόσεων (1)

Abstract Background Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap b...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Felix Grassmann, Christina Kiel, Martina E. Zimmermann, Mathias Gorski, Veronika Grassmann, Klaus Stark, International AMD Genomics Consortium (IAMDGC), Iris M. Heid, Bernhard H. F. Weber
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	BMC 2017-03-01
Σειρά:	Genome Medicine
Θέματα:	Age-related macular degeneration AMD Genetic risk scores GRS Genetic association studies Complex traits
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s13073-017-0418-0

Παρόμοια τεκμήρια

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ανά: Grassmann, F, κ.ά.
Έκδοση: (2017)

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ανά: Elżbieta Nowak, κ.ά.
Έκδοση: (2018-07-01)

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ανά: M. M. Bikbov, κ.ά.
Έκδοση: (2022-03-01)

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Έκδοση: (2023-10-01)

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Έκδοση: (2024-07-01)

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ανά: Ashwin Gupta, κ.ά.
Έκδοση: (2022-01-01)

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Έκδοση: (2025-01-01)

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ανά: Xiang Li, κ.ά.
Έκδοση: (2024-12-01)

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ανά: Treefa Shwani, κ.ά.
Έκδοση: (2023-11-01)

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ανά: Elliott H. Sohn, MD, κ.ά.
Έκδοση: (2021-03-01)

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ανά: S. V. Yanchenko, κ.ά.
Έκδοση: (2023-01-01)

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ανά: Yujong Yi, κ.ά.
Έκδοση: (2024-03-01)

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ανά: Reem H. ElSheikh, κ.ά.
Έκδοση: (2022-11-01)

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ανά: Audrey Yan, κ.ά.
Έκδοση: (2025-01-01)

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ανά: Mayank Choubey, κ.ά.
Έκδοση: (2023-11-01)

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ανά: Zofia Ulańczyk, κ.ά.
Έκδοση: (2020-10-01)

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ανά: Kiruthika M, κ.ά.
Έκδοση: (2025-02-01)

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review
ανά: A. N. Kulikov, κ.ά.
Έκδοση: (2023-10-01)

Early and intermediate age-related macular degeneration: update and clinical review
ανά: García-Layana A, κ.ά.
Έκδοση: (2017-10-01)

Choriocapillaris in Age-Related Macular Degeneration
ανά: Giovanni Neri, κ.ά.
Έκδοση: (2024-08-01)

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration
ανά: Hageman Gregory S, κ.ά.
Έκδοση: (2011-07-01)

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ανά: Amirhossein Roshanshad, κ.ά.
Έκδοση: (2023-11-01)

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ανά: Sacu Stefan, κ.ά.
Έκδοση: (2003-12-01)

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ανά: Răzvan Vasile ROPCIUC
Έκδοση: (2024-05-01)

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ανά: Siin Kim, κ.ά.
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ανά: Ngoc Thien Le, κ.ά.
Έκδοση: (2023-12-01)

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ανά: Grace A. Borchert, κ.ά.
Έκδοση: (2024-07-01)

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ανά: Ines Lains, MD, PhD, κ.ά.
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ανά: Maryam Mousavi, κ.ά.
Έκδοση: (2013-10-01)

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Έκδοση: (2023-05-01)

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