Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Abstract The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread of tumors has opened up new possibilities for the d...

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Bibliographic Details
Main Authors: Mohammad Chehelgerdi, Matin Chehelgerdi, Milad Khorramian-Ghahfarokhi, Marjan Shafieizadeh, Esmaeil Mahmoudi, Fatemeh Eskandari, Mohsen Rashidi, Asghar Arshi, Abbas Mokhtari-Farsani
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Molecular Cancer
Subjects:
CRISPR system
Genome editing
Cancer therapy
Genetic mutations
Tumor growth
Immune response
Online Access:https://doi.org/10.1186/s12943-023-01925-5

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