Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer

Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer

Abstract Background Even though the post-operative outcome varies greatly among patients with nodal positive colon cancer (UICC stage III), personalized prediction of systemic disease recurrence is currently insufficient. We investigated in a retrospective setting whether genetic and immunological b...

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Bibliographic Details
Main Authors: Andreas Sperlich, Alexander Balmert, Dietrich Doll, Sabine Bauer, Fabian Franke, Gisela Keller, Dirk Wilhelm, Anna Mur, Michael Respondek, Helmut Friess, Ulrich Nitsche, Klaus-Peter Janssen
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Chemotherapy
Disease-free survival
Predictors of recurrence
KRAS
BRAF
SASH1
Online Access:http://link.springer.com/article/10.1186/s12885-018-4940-2

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