Relationship between the biomechanical properties of the cornea and anterior segment measurements

OBJECTIVE: To evaluate the relationship of biomechanical properties, corneal hysteresis and corneal resistance factor with age, sex and various corneal parameters measured with a Pentacam in normal subjects. METHODS: A total of 226 eyes from 113 patients were enrolled in this study. The subjects un...

Full description

Bibliographic Details
Main Authors: Murilo Barreto Souza, Fabricio Witzel de Medeiros, Flavio Fernandes Villela, Milton Ruiz Alves
Format: Article
Language:English
Published: Elsevier España 2018-09-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100256&lng=en&tlng=en
_version_ 1828464103477215232
author Murilo Barreto Souza
Fabricio Witzel de Medeiros
Flavio Fernandes Villela
Milton Ruiz Alves
author_facet Murilo Barreto Souza
Fabricio Witzel de Medeiros
Flavio Fernandes Villela
Milton Ruiz Alves
author_sort Murilo Barreto Souza
collection DOAJ
description OBJECTIVE: To evaluate the relationship of biomechanical properties, corneal hysteresis and corneal resistance factor with age, sex and various corneal parameters measured with a Pentacam in normal subjects. METHODS: A total of 226 eyes from 113 patients were enrolled in this study. The subjects underwent Ocular Response Analyzer and Pentacam evaluations. A varying-intercept multilevel regression was implemented using Bayesian inference. The predictor variables were age, sex, central corneal thickness, corneal volume at a 7-mm diameter, anterior chamber angle and volume, anterior chamber depth, mean radius of the corneal curvature and corneal astigmatism. RESULTS: Corneal hysteresis ranged from 5.5 to 14.8 mmHg (mean 10.42±1.74 mmHg), and the corneal resistance factor ranged from 5.7 to 15.5 mmHg (mean 10.23±1.88 mmHg). No predictor variable other than gender and central corneal thickness had a significant correlation with either corneal hysteresis or corneal resistance factor. Corneal hysteresis was positively associated with female sex and with central corneal thickness, and corneal resistance factor was positively associated with central corneal thickness. CONCLUSION: Despite the associations found, only a small fraction of the variance in biomechanical measurements could be explained by the descriptors that were evaluated, indicating the influence of other corneal aspects on the biomechanical characteristics.
first_indexed 2024-12-11T03:07:20Z
format Article
id doaj.art-b0a5316593c64dc78d732375b8aff660
institution Directory Open Access Journal
issn 1980-5322
language English
last_indexed 2024-12-11T03:07:20Z
publishDate 2018-09-01
publisher Elsevier España
record_format Article
series Clinics
spelling doaj.art-b0a5316593c64dc78d732375b8aff6602022-12-22T01:22:56ZengElsevier EspañaClinics1980-53222018-09-0173010.6061/clinics/2018/e491S1807-59322018000100256Relationship between the biomechanical properties of the cornea and anterior segment measurementsMurilo Barreto SouzaFabricio Witzel de MedeirosFlavio Fernandes VillelaMilton Ruiz AlvesOBJECTIVE: To evaluate the relationship of biomechanical properties, corneal hysteresis and corneal resistance factor with age, sex and various corneal parameters measured with a Pentacam in normal subjects. METHODS: A total of 226 eyes from 113 patients were enrolled in this study. The subjects underwent Ocular Response Analyzer and Pentacam evaluations. A varying-intercept multilevel regression was implemented using Bayesian inference. The predictor variables were age, sex, central corneal thickness, corneal volume at a 7-mm diameter, anterior chamber angle and volume, anterior chamber depth, mean radius of the corneal curvature and corneal astigmatism. RESULTS: Corneal hysteresis ranged from 5.5 to 14.8 mmHg (mean 10.42±1.74 mmHg), and the corneal resistance factor ranged from 5.7 to 15.5 mmHg (mean 10.23±1.88 mmHg). No predictor variable other than gender and central corneal thickness had a significant correlation with either corneal hysteresis or corneal resistance factor. Corneal hysteresis was positively associated with female sex and with central corneal thickness, and corneal resistance factor was positively associated with central corneal thickness. CONCLUSION: Despite the associations found, only a small fraction of the variance in biomechanical measurements could be explained by the descriptors that were evaluated, indicating the influence of other corneal aspects on the biomechanical characteristics.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100256&lng=en&tlng=enAnterior Eye SegmentCornealHysteresisScheumpflugBayes
spellingShingle Murilo Barreto Souza
Fabricio Witzel de Medeiros
Flavio Fernandes Villela
Milton Ruiz Alves
Relationship between the biomechanical properties of the cornea and anterior segment measurements
Clinics
Anterior Eye Segment
Corneal
Hysteresis
Scheumpflug
Bayes
title Relationship between the biomechanical properties of the cornea and anterior segment measurements
title_full Relationship between the biomechanical properties of the cornea and anterior segment measurements
title_fullStr Relationship between the biomechanical properties of the cornea and anterior segment measurements
title_full_unstemmed Relationship between the biomechanical properties of the cornea and anterior segment measurements
title_short Relationship between the biomechanical properties of the cornea and anterior segment measurements
title_sort relationship between the biomechanical properties of the cornea and anterior segment measurements
topic Anterior Eye Segment
Corneal
Hysteresis
Scheumpflug
Bayes
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100256&lng=en&tlng=en
work_keys_str_mv AT murilobarretosouza relationshipbetweenthebiomechanicalpropertiesofthecorneaandanteriorsegmentmeasurements
AT fabriciowitzeldemedeiros relationshipbetweenthebiomechanicalpropertiesofthecorneaandanteriorsegmentmeasurements
AT flaviofernandesvillela relationshipbetweenthebiomechanicalpropertiesofthecorneaandanteriorsegmentmeasurements
AT miltonruizalves relationshipbetweenthebiomechanicalpropertiesofthecorneaandanteriorsegmentmeasurements