Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus
The present study aimed to evaluate the effects of quercetin-supplemented in diet on growth, antioxidant capacity and immune response and immune-related gene expression of Channa argus (C. argus) (initial weight, 24.50 ± 0.24 g). A basal diet was supplemented with quercetin at 0, 150, 300 or 450 mg ...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Aquaculture Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513422003106 |
| _version_ | 1828104760192925696 |
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| author | Yuxin Kong Jiaxin Tian Xiaotian Niu Min Li Yidi Kong Ruoming Li Xiumei Chen Guiqin Wang |
| author_facet | Yuxin Kong Jiaxin Tian Xiaotian Niu Min Li Yidi Kong Ruoming Li Xiumei Chen Guiqin Wang |
| author_sort | Yuxin Kong |
| collection | DOAJ |
| description | The present study aimed to evaluate the effects of quercetin-supplemented in diet on growth, antioxidant capacity and immune response and immune-related gene expression of Channa argus (C. argus) (initial weight, 24.50 ± 0.24 g). A basal diet was supplemented with quercetin at 0, 150, 300 or 450 mg kg−1 and feed to C. argus 56 days. Weight gain (WG) and specific growth rate (SGR) were significantly increased (P < .05), and feed conversion ratio (FCR) were significantly decreased (P < .05) with the increase of dietary quercetin levels from 0 to 450 mg kg−1. Supplemented quercetin (150, 300 or 450 mg kg−1) significantly enhanced (P < .05) serum or tissues superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (T-AOC), glutathione S-transferase (GST), glutathione peroxidase (GSH-Px), lysozyme (LZM) activity and complement 3 (C3), complement 4 (C4), immunoglobulin M (IgM) concentration. Meanwhile, quercetin administration significantly up-regulated (P < .05) the expression of immune-related cytokines (interleukin-1β[IL-1β], tumor necrosis factor-α[TNF-α], interleukin-8[IL-8], interleukin-10[IL-10]) in liver, spleen, kidney and intestine of C. argus. These results indicated that dietary supplement quercetin could enhance growth, antioxidant capacity, immune response and regulated immune-related genes expression of C. argus, with greatest effects in C. argus given 300 mg kg−1 quercetin for 56 days. |
| first_indexed | 2024-04-11T09:50:55Z |
| format | Article |
| id | doaj.art-b0a5a49b3f434bd5a55b77ad6efaab97 |
| institution | Directory Open Access Journal |
| issn | 2352-5134 |
| language | English |
| last_indexed | 2024-04-11T09:50:55Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj.art-b0a5a49b3f434bd5a55b77ad6efaab972022-12-22T04:30:47ZengElsevierAquaculture Reports2352-51342022-10-0126101314Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argusYuxin Kong0Jiaxin Tian1Xiaotian Niu2Min Li3Yidi Kong4Ruoming Li5Xiumei Chen6Guiqin Wang7College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China; Corresponding authors at: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China.College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China; Corresponding authors at: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China.The present study aimed to evaluate the effects of quercetin-supplemented in diet on growth, antioxidant capacity and immune response and immune-related gene expression of Channa argus (C. argus) (initial weight, 24.50 ± 0.24 g). A basal diet was supplemented with quercetin at 0, 150, 300 or 450 mg kg−1 and feed to C. argus 56 days. Weight gain (WG) and specific growth rate (SGR) were significantly increased (P < .05), and feed conversion ratio (FCR) were significantly decreased (P < .05) with the increase of dietary quercetin levels from 0 to 450 mg kg−1. Supplemented quercetin (150, 300 or 450 mg kg−1) significantly enhanced (P < .05) serum or tissues superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (T-AOC), glutathione S-transferase (GST), glutathione peroxidase (GSH-Px), lysozyme (LZM) activity and complement 3 (C3), complement 4 (C4), immunoglobulin M (IgM) concentration. Meanwhile, quercetin administration significantly up-regulated (P < .05) the expression of immune-related cytokines (interleukin-1β[IL-1β], tumor necrosis factor-α[TNF-α], interleukin-8[IL-8], interleukin-10[IL-10]) in liver, spleen, kidney and intestine of C. argus. These results indicated that dietary supplement quercetin could enhance growth, antioxidant capacity, immune response and regulated immune-related genes expression of C. argus, with greatest effects in C. argus given 300 mg kg−1 quercetin for 56 days.http://www.sciencedirect.com/science/article/pii/S2352513422003106QuercetinChanna argusGrowthperformance and feed utilizationAntioxidantImmuneresponseImmunegene |
| spellingShingle | Yuxin Kong Jiaxin Tian Xiaotian Niu Min Li Yidi Kong Ruoming Li Xiumei Chen Guiqin Wang Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus Aquaculture Reports Quercetin Channa argus Growthperformance and feed utilization Antioxidant Immuneresponse Immunegene |
| title | Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus |
| title_full | Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus |
| title_fullStr | Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus |
| title_full_unstemmed | Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus |
| title_short | Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus |
| title_sort | effects of dietary quercetin on growth antioxidant capacity immune response and immune related gene expression in snakehead fish channa argus |
| topic | Quercetin Channa argus Growthperformance and feed utilization Antioxidant Immuneresponse Immunegene |
| url | http://www.sciencedirect.com/science/article/pii/S2352513422003106 |
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