Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation.
<h4>Purpose</h4>We previously reported that macular pigment optical density (MPOD) levels decreased during a long follow-up period after clear intraocular lens (IOL) implant surgery presumably due to excessive light exposure. We examined changes in MPOD levels in the eyes that received y...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0248506 |
| _version_ | 1819199445340782592 |
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| author | Akira Obana Yuko Gohto Ryo Asaoka |
| author_facet | Akira Obana Yuko Gohto Ryo Asaoka |
| author_sort | Akira Obana |
| collection | DOAJ |
| description | <h4>Purpose</h4>We previously reported that macular pigment optical density (MPOD) levels decreased during a long follow-up period after clear intraocular lens (IOL) implant surgery presumably due to excessive light exposure. We examined changes in MPOD levels in the eyes that received yellow-tinted IOL implant surgery.<h4>Subjects and methods</h4>This was a prospective, observational study. Fifty-five eyes of 35 patients were studied. MPOD levels were measured with a dual-wavelength autofluorescence technique on day 4; months 1, 3, and 6; and years 1 and 2 postoperatively. The average optical densities at 0°- 2° eccentricities (local MPODs) and total volumes of MPOD (MPOVs) in the area within 1.5° and 9° eccentricities were analyzed.<h4>Results</h4>The mean local MPOD at baseline (on day 4) was 0.79 at 0°, 0.71 at 0.5°, 0.68 at 0.9°, and 0.32 at 2°. The mean MPOV within 1.5° and 9° at baseline was 2950 and 18,897, respectively. Local MPOD at 0.9° and 2° and MPOVs were slightly decreased at month 1 and increased after that. The increase reached statistical significance in local MPOD at 0.5° and 2° and MPOVs (Tukey-Kramer test). The changes in MPOV within 9° at year 2 [(MPOV on year 2 - MPOV on day 4) / MPOV on day 4] were from -0.21 to 1.18 (mean and standard deviation: 1.14 ± 0.28). The MPOV of 15 eyes increased more than 10% from the initial value, was maintained within 10% in 21 eyes, and deteriorated more than 10% in only 3 eyes.<h4>Conclusions</h4>Local MPOD and MPOV tended to slightly decrease month 1 postoperatively and gradually increased after that, but the rates of increases in MPOD levels were small. Yellow-tinted IOLs that have a lower transmittance of blue light might be preferable for preserving MPOD levels after surgery. |
| first_indexed | 2024-12-23T03:16:27Z |
| format | Article |
| id | doaj.art-b0a677515d8e4b85a81eb847b55c3e55 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-23T03:16:27Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b0a677515d8e4b85a81eb847b55c3e552022-12-21T18:02:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024850610.1371/journal.pone.0248506Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation.Akira ObanaYuko GohtoRyo Asaoka<h4>Purpose</h4>We previously reported that macular pigment optical density (MPOD) levels decreased during a long follow-up period after clear intraocular lens (IOL) implant surgery presumably due to excessive light exposure. We examined changes in MPOD levels in the eyes that received yellow-tinted IOL implant surgery.<h4>Subjects and methods</h4>This was a prospective, observational study. Fifty-five eyes of 35 patients were studied. MPOD levels were measured with a dual-wavelength autofluorescence technique on day 4; months 1, 3, and 6; and years 1 and 2 postoperatively. The average optical densities at 0°- 2° eccentricities (local MPODs) and total volumes of MPOD (MPOVs) in the area within 1.5° and 9° eccentricities were analyzed.<h4>Results</h4>The mean local MPOD at baseline (on day 4) was 0.79 at 0°, 0.71 at 0.5°, 0.68 at 0.9°, and 0.32 at 2°. The mean MPOV within 1.5° and 9° at baseline was 2950 and 18,897, respectively. Local MPOD at 0.9° and 2° and MPOVs were slightly decreased at month 1 and increased after that. The increase reached statistical significance in local MPOD at 0.5° and 2° and MPOVs (Tukey-Kramer test). The changes in MPOV within 9° at year 2 [(MPOV on year 2 - MPOV on day 4) / MPOV on day 4] were from -0.21 to 1.18 (mean and standard deviation: 1.14 ± 0.28). The MPOV of 15 eyes increased more than 10% from the initial value, was maintained within 10% in 21 eyes, and deteriorated more than 10% in only 3 eyes.<h4>Conclusions</h4>Local MPOD and MPOV tended to slightly decrease month 1 postoperatively and gradually increased after that, but the rates of increases in MPOD levels were small. Yellow-tinted IOLs that have a lower transmittance of blue light might be preferable for preserving MPOD levels after surgery.https://doi.org/10.1371/journal.pone.0248506 |
| spellingShingle | Akira Obana Yuko Gohto Ryo Asaoka Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. PLoS ONE |
| title | Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. |
| title_full | Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. |
| title_fullStr | Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. |
| title_full_unstemmed | Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. |
| title_short | Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation. |
| title_sort | macular pigment changes after cataract surgery with yellow tinted intraocular lens implantation |
| url | https://doi.org/10.1371/journal.pone.0248506 |
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