BODIPY-Based Molecules for Biomedical Applications
BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagnetic spectrum, (2) strong fluo...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/13/12/1723 |
| _version_ | 1797381887355781120 |
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| author | Sarasija Das Sudipto Dey Sanujit Patra Arindam Bera Totan Ghosh Bibin Prasad Kapil Dev Sayala Krishnendu Maji Anjan Bedi Sashi Debnath |
| author_facet | Sarasija Das Sudipto Dey Sanujit Patra Arindam Bera Totan Ghosh Bibin Prasad Kapil Dev Sayala Krishnendu Maji Anjan Bedi Sashi Debnath |
| author_sort | Sarasija Das |
| collection | DOAJ |
| description | BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagnetic spectrum, (2) strong fluorescence and (3) supreme photostability. They have also been employed in areas like photodynamic therapy. Over the last decade, BODIPY-based molecules have even emerged as candidates for cancer treatments. Cancer remains a significant health issue world-wide, necessitating a continuing search for novel therapeutic options. BODIPY is a flexible fluorophore with distinct photophysical characteristics and is a fascinating drug development platform. This review provides a comprehensive overview of the most recent breakthroughs in BODIPY-based small molecules for cancer or disease detection and therapy, including their functional potential. |
| first_indexed | 2024-03-08T20:57:58Z |
| format | Article |
| id | doaj.art-b0a949a4d6a343f49e8dfb490358c107 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-08T20:57:58Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-b0a949a4d6a343f49e8dfb490358c1072023-12-22T13:55:54ZengMDPI AGBiomolecules2218-273X2023-11-011312172310.3390/biom13121723BODIPY-Based Molecules for Biomedical ApplicationsSarasija Das0Sudipto Dey1Sanujit Patra2Arindam Bera3Totan Ghosh4Bibin Prasad5Kapil Dev Sayala6Krishnendu Maji7Anjan Bedi8Sashi Debnath9Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USADepartment of Chemistry, Jadavpur University, Jadavpur, Kolkata 700032, IndiaDepartment of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Nadia 741249, IndiaDepartment of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Nadia 741249, IndiaDepartment of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Nadia 741249, IndiaSolenic Medical, Inc., 4275 Kellway Circle, Suite 146, Addison, TX 75001, USADepartment of Chemistry, Southern Methodist University, 3215 Daniel Avenue, Dallas, TX 75206, USADepartment of Applied Chemistry, Maulana Abul Kalam Azad University of Technology, Nadia 741249, IndiaDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USABODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagnetic spectrum, (2) strong fluorescence and (3) supreme photostability. They have also been employed in areas like photodynamic therapy. Over the last decade, BODIPY-based molecules have even emerged as candidates for cancer treatments. Cancer remains a significant health issue world-wide, necessitating a continuing search for novel therapeutic options. BODIPY is a flexible fluorophore with distinct photophysical characteristics and is a fascinating drug development platform. This review provides a comprehensive overview of the most recent breakthroughs in BODIPY-based small molecules for cancer or disease detection and therapy, including their functional potential.https://www.mdpi.com/2218-273X/13/12/1723BODIPYBODIPY dyesfluorescent probeBODIPY-based functional materials for medical use |
| spellingShingle | Sarasija Das Sudipto Dey Sanujit Patra Arindam Bera Totan Ghosh Bibin Prasad Kapil Dev Sayala Krishnendu Maji Anjan Bedi Sashi Debnath BODIPY-Based Molecules for Biomedical Applications Biomolecules BODIPY BODIPY dyes fluorescent probe BODIPY-based functional materials for medical use |
| title | BODIPY-Based Molecules for Biomedical Applications |
| title_full | BODIPY-Based Molecules for Biomedical Applications |
| title_fullStr | BODIPY-Based Molecules for Biomedical Applications |
| title_full_unstemmed | BODIPY-Based Molecules for Biomedical Applications |
| title_short | BODIPY-Based Molecules for Biomedical Applications |
| title_sort | bodipy based molecules for biomedical applications |
| topic | BODIPY BODIPY dyes fluorescent probe BODIPY-based functional materials for medical use |
| url | https://www.mdpi.com/2218-273X/13/12/1723 |
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