Parathyroid carcinoma masquerading as morning sickness in pregnancy
Incidence of primary hyperparathyroidism (PHP) in pregnancy is 8/100,000 population/year with less than 200 cases reported. Physiological changes associated with pregnancy make a diagnosis of PHP difficult and 80% are asymptomatic. High index of suspicion is required as physiological hypocalcemia re...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=7;spage=198;epage=200;aulast=Panchani |
| _version_ | 1818019888822747136 |
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| author | Roopal Panchani Tarun Varma Ashutosh Goyal Sudhir Tripathi |
| author_facet | Roopal Panchani Tarun Varma Ashutosh Goyal Sudhir Tripathi |
| author_sort | Roopal Panchani |
| collection | DOAJ |
| description | Incidence of primary hyperparathyroidism (PHP) in pregnancy is 8/100,000 population/year with less than 200 cases reported. Physiological changes associated with pregnancy make a diagnosis of PHP difficult and 80% are asymptomatic. High index of suspicion is required as physiological hypocalcemia related to hemodilution, increased glomerular filtration rate resulting in maternal hypercalciuria and gestational hypoalbuminemia can mask hypercalcemia of PHP. Maternal and fetal complication rates are high. Early recognition followed by appropriate management and treatment significantly reduces complications. Here, we present a rare case of parathyroid carcinoma in pregnancy and highlight the difficulties in diagnosis given the non-specific symptoms related to hypercalcemia. We have also discussed the management of PHP during the pregnancy. PHP is a preventable cause of fetal and maternal morbidity and mortality. |
| first_indexed | 2024-04-14T07:57:47Z |
| format | Article |
| id | doaj.art-b0ad048345d14c8da6e4138af7442d44 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-04-14T07:57:47Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-b0ad048345d14c8da6e4138af7442d442022-12-22T02:04:59ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002013-01-0117719820010.4103/2230-8210.119570Parathyroid carcinoma masquerading as morning sickness in pregnancyRoopal PanchaniTarun VarmaAshutosh GoyalSudhir TripathiIncidence of primary hyperparathyroidism (PHP) in pregnancy is 8/100,000 population/year with less than 200 cases reported. Physiological changes associated with pregnancy make a diagnosis of PHP difficult and 80% are asymptomatic. High index of suspicion is required as physiological hypocalcemia related to hemodilution, increased glomerular filtration rate resulting in maternal hypercalciuria and gestational hypoalbuminemia can mask hypercalcemia of PHP. Maternal and fetal complication rates are high. Early recognition followed by appropriate management and treatment significantly reduces complications. Here, we present a rare case of parathyroid carcinoma in pregnancy and highlight the difficulties in diagnosis given the non-specific symptoms related to hypercalcemia. We have also discussed the management of PHP during the pregnancy. PHP is a preventable cause of fetal and maternal morbidity and mortality.http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=7;spage=198;epage=200;aulast=PanchaniHypercalcemiahyperparathyroidism in pregnancymorning sicknessparathyroid carcinoma |
| spellingShingle | Roopal Panchani Tarun Varma Ashutosh Goyal Sudhir Tripathi Parathyroid carcinoma masquerading as morning sickness in pregnancy Indian Journal of Endocrinology and Metabolism Hypercalcemia hyperparathyroidism in pregnancy morning sickness parathyroid carcinoma |
| title | Parathyroid carcinoma masquerading as morning sickness in pregnancy |
| title_full | Parathyroid carcinoma masquerading as morning sickness in pregnancy |
| title_fullStr | Parathyroid carcinoma masquerading as morning sickness in pregnancy |
| title_full_unstemmed | Parathyroid carcinoma masquerading as morning sickness in pregnancy |
| title_short | Parathyroid carcinoma masquerading as morning sickness in pregnancy |
| title_sort | parathyroid carcinoma masquerading as morning sickness in pregnancy |
| topic | Hypercalcemia hyperparathyroidism in pregnancy morning sickness parathyroid carcinoma |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=7;spage=198;epage=200;aulast=Panchani |
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