Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300
Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous positive airway p...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2022-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/428357 |
| Summary: | Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized
by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied
by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous
positive airway pressure (CPAP), weight loss, positional therapy, oral appliances, hypoglossal nerve
stimulation, and surgical procedures. It has been observed that untreated OSA is related to chronic
disorders including hypertension, arrhythmias, congestive heart failure, coronary heart disease, diabetes
mellitus, hyperlipidemia, stroke, depression, and cognitive decline. Event-related potentials (ERPs)
is the procedure that has been widely used for evaluating cognitive brain functions. Using auditory
event-related potentials (P300), this study aimed to examine the effect of CPAP therapy on cognitive
functions in patients with moderate and severe OSA. The results of the study showed improvement
in P300 latency and amplitude after 3 months of CPAP therapy, indicating a positive effect of CPAP
therapy in the prevention of cognitive decline in patients with OSA. |
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| ISSN: | 0353-9466 1333-9451 |