Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300
Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous positive airway p...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2022-01-01
|
| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/428357 |
| _version_ | 1827281874100158464 |
|---|---|
| author | Jelena Šarić Jurić Stjepan Jurić Ivana Marković |
| author_facet | Jelena Šarić Jurić Stjepan Jurić Ivana Marković |
| author_sort | Jelena Šarić Jurić |
| collection | DOAJ |
| description | Obstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized
by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied
by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous
positive airway pressure (CPAP), weight loss, positional therapy, oral appliances, hypoglossal nerve
stimulation, and surgical procedures. It has been observed that untreated OSA is related to chronic
disorders including hypertension, arrhythmias, congestive heart failure, coronary heart disease, diabetes
mellitus, hyperlipidemia, stroke, depression, and cognitive decline. Event-related potentials (ERPs)
is the procedure that has been widely used for evaluating cognitive brain functions. Using auditory
event-related potentials (P300), this study aimed to examine the effect of CPAP therapy on cognitive
functions in patients with moderate and severe OSA. The results of the study showed improvement
in P300 latency and amplitude after 3 months of CPAP therapy, indicating a positive effect of CPAP
therapy in the prevention of cognitive decline in patients with OSA. |
| first_indexed | 2024-04-24T09:08:33Z |
| format | Article |
| id | doaj.art-b0b2a9c8a06c40b2855c4b072795669d |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:08:33Z |
| publishDate | 2022-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-b0b2a9c8a06c40b2855c4b072795669d2024-04-15T18:21:11ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512022-01-0161.337337810.20471/acc.2022.61.03.01Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300Jelena Šarić Jurić0Stjepan Jurić1Ivana Marković2Department of Neurology, University Hospital Center Osijek, Osijek, Croatia; Department of Neurology and Neurosurgery, Faculty of Medicine Osijek, J. J. Strossmayer University, Osijek, Croatia; Department of Neurology and Neurosurgery, Faculty of Dental Medicine and Health, J. J. Strossmayer University, Osijek, CroatiaDepartment of Neurology, University Hospital Center Osijek, Osijek, Croatia; Department of Neurology and Neurosurgery, Faculty of Medicine Osijek, J. J. Strossmayer University, Osijek, Croatia; Department of Neurology and Neurosurgery, Faculty of Dental Medicine and Health, J. J. Strossmayer University, Osijek, CroatiaDepartment of Neurology, University Hospital Center Osijek, Osijek, Croatia; Department of Neurology and Neurosurgery, Faculty of Dental Medicine and Health, J. J. Strossmayer University, Osijek, Croatia; Department of Neurology, University hospital Dubrava, Zagreb, CroatiaObstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous positive airway pressure (CPAP), weight loss, positional therapy, oral appliances, hypoglossal nerve stimulation, and surgical procedures. It has been observed that untreated OSA is related to chronic disorders including hypertension, arrhythmias, congestive heart failure, coronary heart disease, diabetes mellitus, hyperlipidemia, stroke, depression, and cognitive decline. Event-related potentials (ERPs) is the procedure that has been widely used for evaluating cognitive brain functions. Using auditory event-related potentials (P300), this study aimed to examine the effect of CPAP therapy on cognitive functions in patients with moderate and severe OSA. The results of the study showed improvement in P300 latency and amplitude after 3 months of CPAP therapy, indicating a positive effect of CPAP therapy in the prevention of cognitive decline in patients with OSA.https://hrcak.srce.hr/file/428357Obstructive Sleep ApneaContinuous Positive Airway PressureAuditory Event-related PotentialsP300 |
| spellingShingle | Jelena Šarić Jurić Stjepan Jurić Ivana Marković Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 Acta Clinica Croatica Obstructive Sleep Apnea Continuous Positive Airway Pressure Auditory Event-related Potentials P300 |
| title | Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 |
| title_full | Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 |
| title_fullStr | Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 |
| title_full_unstemmed | Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 |
| title_short | Influence of Continuous Positive Airway Pressure Treatment on Auditory Event-Related Potentials P300 |
| title_sort | influence of continuous positive airway pressure treatment on auditory event related potentials p300 |
| topic | Obstructive Sleep Apnea Continuous Positive Airway Pressure Auditory Event-related Potentials P300 |
| url | https://hrcak.srce.hr/file/428357 |
| work_keys_str_mv | AT jelenasaricjuric influenceofcontinuouspositiveairwaypressuretreatmentonauditoryeventrelatedpotentialsp300 AT stjepanjuric influenceofcontinuouspositiveairwaypressuretreatmentonauditoryeventrelatedpotentialsp300 AT ivanamarkovic influenceofcontinuouspositiveairwaypressuretreatmentonauditoryeventrelatedpotentialsp300 |