Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach

Abstract Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in western countries. The association between CLL and glomerular disease (GD) is rare. The most frequent GD associated with CLL is membranoproliferative membranous glomerulonephritis (GN) (MPGN) (45%) types I and II, fol...

Full description

Bibliographic Details
Main Authors: Angela Rago, Laura Pettorini, Alessandro Andriani, Tommaso Caravita di Toritto
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:eJHaem
Subjects:
Online Access:https://doi.org/10.1002/jha2.592
_version_ 1827318954529390592
author Angela Rago
Laura Pettorini
Alessandro Andriani
Tommaso Caravita di Toritto
author_facet Angela Rago
Laura Pettorini
Alessandro Andriani
Tommaso Caravita di Toritto
author_sort Angela Rago
collection DOAJ
description Abstract Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in western countries. The association between CLL and glomerular disease (GD) is rare. The most frequent GD associated with CLL is membranoproliferative membranous glomerulonephritis (GN) (MPGN) (45%) types I and II, followed by membranous glomerulonephritis, with the same reports of immunotactoid glomerulopathy (ITG). We report a case of ITG diagnosed on kidney biopsy in a CLL patient and the response of renal parameters to drug treatment for CLL. The patient was treated with several lines of therapies with a good response.
first_indexed 2024-03-12T14:06:55Z
format Article
id doaj.art-b0bb8dfbd4f74850b1e4c2367bfcfdd9
institution Directory Open Access Journal
issn 2688-6146
language English
last_indexed 2024-04-25T00:10:29Z
publishDate 2023-02-01
publisher Wiley
record_format Article
series eJHaem
spelling doaj.art-b0bb8dfbd4f74850b1e4c2367bfcfdd92024-03-13T13:30:48ZengWileyeJHaem2688-61462023-02-014126626810.1002/jha2.592Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approachAngela Rago0Laura Pettorini1Alessandro Andriani2Tommaso Caravita di Toritto3Haematology Unit, ASL ROMA 1 Santo Spirito Hospital of Rome Rome ItalyNefrology Unit, ASL ROMA 1 Santo Spirito of Rome Rome ItalyInternal Medicine Villa Betania Hospital Rome ItalyHaematology Unit, ASL ROMA 1 Santo Spirito Hospital of Rome Rome ItalyAbstract Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in western countries. The association between CLL and glomerular disease (GD) is rare. The most frequent GD associated with CLL is membranoproliferative membranous glomerulonephritis (GN) (MPGN) (45%) types I and II, followed by membranous glomerulonephritis, with the same reports of immunotactoid glomerulopathy (ITG). We report a case of ITG diagnosed on kidney biopsy in a CLL patient and the response of renal parameters to drug treatment for CLL. The patient was treated with several lines of therapies with a good response.https://doi.org/10.1002/jha2.592chronic lymphocytic leukemiaimmunotactoid glomerulopathy
spellingShingle Angela Rago
Laura Pettorini
Alessandro Andriani
Tommaso Caravita di Toritto
Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
eJHaem
chronic lymphocytic leukemia
immunotactoid glomerulopathy
title Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
title_full Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
title_fullStr Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
title_full_unstemmed Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
title_short Immunotactoid glomerulopathy and chronic lymphocytic leukemia: The need for a multidisciplinary approach
title_sort immunotactoid glomerulopathy and chronic lymphocytic leukemia the need for a multidisciplinary approach
topic chronic lymphocytic leukemia
immunotactoid glomerulopathy
url https://doi.org/10.1002/jha2.592
work_keys_str_mv AT angelarago immunotactoidglomerulopathyandchroniclymphocyticleukemiatheneedforamultidisciplinaryapproach
AT laurapettorini immunotactoidglomerulopathyandchroniclymphocyticleukemiatheneedforamultidisciplinaryapproach
AT alessandroandriani immunotactoidglomerulopathyandchroniclymphocyticleukemiatheneedforamultidisciplinaryapproach
AT tommasocaravitaditoritto immunotactoidglomerulopathyandchroniclymphocyticleukemiatheneedforamultidisciplinaryapproach