Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis
Background: Urinary tract infection (UTI) is one of the most common infectious diseases ranking next to upper respiratory tract infections. UTIs are often significantly associated with morbidity and mortality. The inappropriate administration of antibiotics to treat these infections increased infect...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=169;epage=169;aulast=Reza |
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| author | Seyed Abdol Reza Mortazavi-Tabatabaei Jalal Ghaderkhani Ali Nazari Kourosh Sayehmiri Fatemeh Sayehmiri Iraj Pakzad |
| author_facet | Seyed Abdol Reza Mortazavi-Tabatabaei Jalal Ghaderkhani Ali Nazari Kourosh Sayehmiri Fatemeh Sayehmiri Iraj Pakzad |
| author_sort | Seyed Abdol Reza Mortazavi-Tabatabaei |
| collection | DOAJ |
| description | Background: Urinary tract infection (UTI) is one of the most common infectious diseases ranking next to upper respiratory tract infections. UTIs are often significantly associated with morbidity and mortality. The inappropriate administration of antibiotics to treat these infections increased infection resistance to antibiotics. The aim of this study is to determine the frequency of antibiotic resistance pattern in UTIs. Methods: We searched several databases including PubMed, Web of Science, Scopus, Google Scholar, Iran Medex, Magiran, IranDoc, MedLib, and Scientific Information Database to identify the studies addressing antibacterial resistance patterns of the most common uropathogenic bacteria in UTIs in Iran. A total of 90 reports published from different regions of Iran from 1992 to May 2015 were involved in this study. Results: It is shown that the most common pathogen causing UTIs is Escherichia coli with 62%. The resistance among the isolates of E. coli was as follows: ampicillin (86%), amoxicillin (76%), tetracycline (71%), trimethoprim-sulfamethoxazole (64%), cephalexin (61%), and cefalothin (60%). The highest sensitivity among isolates of E. coli was as follows: imipenem (86%), nitrofurantoin (82%), amikacin (79%), chloramphenicol (72%), and ciprofloxacin (72%). Conclusions: The results of this study showed that the most common resistance are antibiotics that are commonly used. The most effective antibiotics for E. coli were imipenem, nitrofurantoin, amikacin, chloramphenicol, and ciprofloxacin. Considering this study, it had better, use less gentamicin, second-generation cephalosporins, and nalidixic acid in the initial treatment of infections caused by E. coli, and no use penicillins, tetracyclines, cotrimoxazole, and first-generation cephalosporins. |
| first_indexed | 2024-04-14T07:34:14Z |
| format | Article |
| id | doaj.art-b0bc16bf4b154044bb1598c5c895c51a |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-04-14T07:34:14Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-b0bc16bf4b154044bb1598c5c895c51a2022-12-22T02:05:44ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132019-01-0110116916910.4103/ijpvm.IJPVM_419_17Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysisSeyed Abdol Reza Mortazavi-TabatabaeiJalal GhaderkhaniAli NazariKourosh SayehmiriFatemeh SayehmiriIraj PakzadBackground: Urinary tract infection (UTI) is one of the most common infectious diseases ranking next to upper respiratory tract infections. UTIs are often significantly associated with morbidity and mortality. The inappropriate administration of antibiotics to treat these infections increased infection resistance to antibiotics. The aim of this study is to determine the frequency of antibiotic resistance pattern in UTIs. Methods: We searched several databases including PubMed, Web of Science, Scopus, Google Scholar, Iran Medex, Magiran, IranDoc, MedLib, and Scientific Information Database to identify the studies addressing antibacterial resistance patterns of the most common uropathogenic bacteria in UTIs in Iran. A total of 90 reports published from different regions of Iran from 1992 to May 2015 were involved in this study. Results: It is shown that the most common pathogen causing UTIs is Escherichia coli with 62%. The resistance among the isolates of E. coli was as follows: ampicillin (86%), amoxicillin (76%), tetracycline (71%), trimethoprim-sulfamethoxazole (64%), cephalexin (61%), and cefalothin (60%). The highest sensitivity among isolates of E. coli was as follows: imipenem (86%), nitrofurantoin (82%), amikacin (79%), chloramphenicol (72%), and ciprofloxacin (72%). Conclusions: The results of this study showed that the most common resistance are antibiotics that are commonly used. The most effective antibiotics for E. coli were imipenem, nitrofurantoin, amikacin, chloramphenicol, and ciprofloxacin. Considering this study, it had better, use less gentamicin, second-generation cephalosporins, and nalidixic acid in the initial treatment of infections caused by E. coli, and no use penicillins, tetracyclines, cotrimoxazole, and first-generation cephalosporins.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=169;epage=169;aulast=Rezaantibioticsantimicrobial resistancegram-negative bacteriagram-positive bacteriaurinary tract infections |
| spellingShingle | Seyed Abdol Reza Mortazavi-Tabatabaei Jalal Ghaderkhani Ali Nazari Kourosh Sayehmiri Fatemeh Sayehmiri Iraj Pakzad Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis International Journal of Preventive Medicine antibiotics antimicrobial resistance gram-negative bacteria gram-positive bacteria urinary tract infections |
| title | Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis |
| title_full | Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis |
| title_fullStr | Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis |
| title_full_unstemmed | Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis |
| title_short | Pattern of antibacterial resistance in urinary tract infections: A systematic review and meta-analysis |
| title_sort | pattern of antibacterial resistance in urinary tract infections a systematic review and meta analysis |
| topic | antibiotics antimicrobial resistance gram-negative bacteria gram-positive bacteria urinary tract infections |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=169;epage=169;aulast=Reza |
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