Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level
Mastocytosis is a rare group of disorders characterized by abnormal accumulation of mast cells in the skin, bone marrow, and internal organs. In particular, patients with systemic mastocytosis are at an increased risk of frequent and severe episodes of anaphylaxis. Hymenoptera venom allergy is the m...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-06-01
|
| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2020.1846398 |
| _version_ | 1797677234016747520 |
|---|---|
| author | Ali Selcuk Abdullah Baysan |
| author_facet | Ali Selcuk Abdullah Baysan |
| author_sort | Ali Selcuk |
| collection | DOAJ |
| description | Mastocytosis is a rare group of disorders characterized by abnormal accumulation of mast cells in the skin, bone marrow, and internal organs. In particular, patients with systemic mastocytosis are at an increased risk of frequent and severe episodes of anaphylaxis. Hymenoptera venom allergy is the most common trigger of anaphylaxis in these patients. Immunotherapy is an effective and safe therapy recommended for patients with mastocytosis and venom allergy. Although this therapy can be administered according to different protocols, the preferred protocol for patients with mastocytosis remains unclear. Systemic side effects can occur, in particular, during the up-dosing phase of immunotherapy, making progression to the maintenance phase of therapy challenging. This case report presents the diagnosis and ultrarush immunotherapy process ended with anaphylaxis of a 33-y-old male patient with Apis mellifera allergy. |
| first_indexed | 2024-03-11T22:42:06Z |
| format | Article |
| id | doaj.art-b0c0cecb5a28460883bf70096799fb75 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:42:06Z |
| publishDate | 2021-06-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-b0c0cecb5a28460883bf70096799fb752023-09-22T08:51:52ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-06-011761599160310.1080/21645515.2020.18463981846398Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase levelAli Selcuk0Abdullah Baysan1Malatya Training and Research HospitalUniversity of Health SciencesMastocytosis is a rare group of disorders characterized by abnormal accumulation of mast cells in the skin, bone marrow, and internal organs. In particular, patients with systemic mastocytosis are at an increased risk of frequent and severe episodes of anaphylaxis. Hymenoptera venom allergy is the most common trigger of anaphylaxis in these patients. Immunotherapy is an effective and safe therapy recommended for patients with mastocytosis and venom allergy. Although this therapy can be administered according to different protocols, the preferred protocol for patients with mastocytosis remains unclear. Systemic side effects can occur, in particular, during the up-dosing phase of immunotherapy, making progression to the maintenance phase of therapy challenging. This case report presents the diagnosis and ultrarush immunotherapy process ended with anaphylaxis of a 33-y-old male patient with Apis mellifera allergy.http://dx.doi.org/10.1080/21645515.2020.1846398anaphylaxishoneybeehymenoptera venom allergyimmunotherapymastocytosistryptase |
| spellingShingle | Ali Selcuk Abdullah Baysan Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level Human Vaccines & Immunotherapeutics anaphylaxis honeybee hymenoptera venom allergy immunotherapy mastocytosis tryptase |
| title | Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| title_full | Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| title_fullStr | Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| title_full_unstemmed | Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| title_short | Venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| title_sort | venom immunotherapy in indolent systemic mastocytosis with high serum tryptase level |
| topic | anaphylaxis honeybee hymenoptera venom allergy immunotherapy mastocytosis tryptase |
| url | http://dx.doi.org/10.1080/21645515.2020.1846398 |
| work_keys_str_mv | AT aliselcuk venomimmunotherapyinindolentsystemicmastocytosiswithhighserumtryptaselevel AT abdullahbaysan venomimmunotherapyinindolentsystemicmastocytosiswithhighserumtryptaselevel |