Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells

Human amnion is a favorable potential source of mesenchymal stem cells (MSC) for future cell-therapy-based clinical applications, because of the painless collection procedure and easy accessibility of the placenta. Human amnion mesenchymal stem cells (hAMCs) have multilineage differentiation ability...

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Main Authors: Fiona Macniesia Thomas, Sandra Lisa Gumpil, Siti Fatimah Simat, Vijay Kumar Subbiah
Format: Article
Language:English
Published: Compuscript Ltd 2022-12-01
Series:BIO Integration
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/cscript/bioi/2022/00000003/00000004/art00004
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author Fiona Macniesia Thomas
Sandra Lisa Gumpil
Siti Fatimah Simat
Vijay Kumar Subbiah
author_facet Fiona Macniesia Thomas
Sandra Lisa Gumpil
Siti Fatimah Simat
Vijay Kumar Subbiah
author_sort Fiona Macniesia Thomas
collection DOAJ
description Human amnion is a favorable potential source of mesenchymal stem cells (MSC) for future cell-therapy-based clinical applications, because of the painless collection procedure and easy accessibility of the placenta. Human amnion mesenchymal stem cells (hAMCs) have multilineage differentiation ability and high proliferation ability, are non-tumorigenic and have a relatively low risk of rejection after transplantation. Given the beneficial properties of hAMCs, herein, we review the isolation methods and characteristics of hAMCs. Furthermore, we summarize current hAMC applications and preservation methods.
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spelling doaj.art-b0c0eabb2af849a4864d9f2296fecc142023-03-07T07:43:32ZengCompuscript LtdBIO Integration2712-00822022-12-013417217910.15212/bioi-2022-0017Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem CellsFiona Macniesia Thomas0Sandra Lisa Gumpil1Siti Fatimah Simat2Vijay Kumar Subbiah3Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MalaysiaBiotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MalaysiaBiotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MalaysiaBiotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MalaysiaHuman amnion is a favorable potential source of mesenchymal stem cells (MSC) for future cell-therapy-based clinical applications, because of the painless collection procedure and easy accessibility of the placenta. Human amnion mesenchymal stem cells (hAMCs) have multilineage differentiation ability and high proliferation ability, are non-tumorigenic and have a relatively low risk of rejection after transplantation. Given the beneficial properties of hAMCs, herein, we review the isolation methods and characteristics of hAMCs. Furthermore, we summarize current hAMC applications and preservation methods.https://www.ingentaconnect.com/contentone/cscript/bioi/2022/00000003/00000004/art00004cell culturecell preservationhuman amnion mesenchymal stem cellstem cells
spellingShingle Fiona Macniesia Thomas
Sandra Lisa Gumpil
Siti Fatimah Simat
Vijay Kumar Subbiah
Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
BIO Integration
cell culture
cell preservation
human amnion mesenchymal stem cell
stem cells
title Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
title_full Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
title_fullStr Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
title_full_unstemmed Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
title_short Isolation, Characteristics, Differentiation and Exploitation of Human Amnion Mesenchymal Stem Cells
title_sort isolation characteristics differentiation and exploitation of human amnion mesenchymal stem cells
topic cell culture
cell preservation
human amnion mesenchymal stem cell
stem cells
url https://www.ingentaconnect.com/contentone/cscript/bioi/2022/00000003/00000004/art00004
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AT sandralisagumpil isolationcharacteristicsdifferentiationandexploitationofhumanamnionmesenchymalstemcells
AT sitifatimahsimat isolationcharacteristicsdifferentiationandexploitationofhumanamnionmesenchymalstemcells
AT vijaykumarsubbiah isolationcharacteristicsdifferentiationandexploitationofhumanamnionmesenchymalstemcells