Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)

In order to prevent the resistance of Anopheles gambiae s.l. to pyrethroids from spreading too quickly and to lengthen the effectiveness of insecticide impregnated mosquito nets, it has recently been suggested to use mixtures of insecticides that have different modes of action. This study presents t...

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Main Authors: Darriet F., Corbel V., Hougard J.M.
Format: Article
Language:English
Published: EDP Sciences 2003-12-01
Series:Parasite
Subjects:
Online Access:http://dx.doi.org/10.1051/parasite/2003104359
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author Darriet F.
Corbel V.
Hougard J.M.
author_facet Darriet F.
Corbel V.
Hougard J.M.
author_sort Darriet F.
collection DOAJ
description In order to prevent the resistance of Anopheles gambiae s.l. to pyrethroids from spreading too quickly and to lengthen the effectiveness of insecticide impregnated mosquito nets, it has recently been suggested to use mixtures of insecticides that have different modes of action. This study presents the results obtained with tulle mosquito nets treated with bifenthrin (a pyrethroid] and chlorpyrifos-methyl (an organophosphorous) both separately and in mixture on two strains of An. gambiae, one sensitive to all insecticides, and the other resistant to pyrethroids. The values of KDt50 and KDt95 and the mortality induced with the mixture of bifenthrin (25 mg/m2 ) and chlorpyrifos-methyl (4.5 mg/m2 ) show a significant synergistic effect on the strain of An. gambiae susceptible to insecticides. However, the tested combination does not induce any synergistic effect on the VKPR strain selected with permethrin, but only enhances the effectiveness of the two insecticides taken separately.
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spelling doaj.art-b0c5714fd7824adc86439bbd766c51072023-12-03T04:30:28ZengEDP SciencesParasite1252-607X1776-10422003-12-0110435936210.1051/parasite/2003104359parasite2003104p359Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)Darriet F.Corbel V.Hougard J.M.In order to prevent the resistance of Anopheles gambiae s.l. to pyrethroids from spreading too quickly and to lengthen the effectiveness of insecticide impregnated mosquito nets, it has recently been suggested to use mixtures of insecticides that have different modes of action. This study presents the results obtained with tulle mosquito nets treated with bifenthrin (a pyrethroid] and chlorpyrifos-methyl (an organophosphorous) both separately and in mixture on two strains of An. gambiae, one sensitive to all insecticides, and the other resistant to pyrethroids. The values of KDt50 and KDt95 and the mortality induced with the mixture of bifenthrin (25 mg/m2 ) and chlorpyrifos-methyl (4.5 mg/m2 ) show a significant synergistic effect on the strain of An. gambiae susceptible to insecticides. However, the tested combination does not induce any synergistic effect on the VKPR strain selected with permethrin, but only enhances the effectiveness of the two insecticides taken separately.http://dx.doi.org/10.1051/parasite/2003104359bifenthrinchlorpyrifos-methylsynergymosquito netAnophelesgambiae
spellingShingle Darriet F.
Corbel V.
Hougard J.M.
Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
Parasite
bifenthrin
chlorpyrifos-methyl
synergy
mosquito net
Anophelesgambiae
title Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
title_full Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
title_fullStr Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
title_full_unstemmed Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
title_short Efficacy of mosquito nets treated with a pyrethroid-organophosphorous mixture against Kdr- and Kdr+ malaria vectors (Anopheles gambiae)
title_sort efficacy of mosquito nets treated with a pyrethroid organophosphorous mixture against kdr and kdr malaria vectors anopheles gambiae
topic bifenthrin
chlorpyrifos-methyl
synergy
mosquito net
Anophelesgambiae
url http://dx.doi.org/10.1051/parasite/2003104359
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