POGZ suppresses 2C transcriptional program and retrotransposable elements

Summary: The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and intellectual disability (ID). We have recently shown that POGZ maintains mouse embryonic stem cells (ESCs). However, the exact mechanisms remain unclear. Here, w...

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Bibliographic Details
Main Authors: Xiaoyun Sun, Tianzhe Zhang, Bei Tong, Linxi Cheng, Wei Jiang, Yuhua Sun
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723008781