Proliferative vitreoretinopathy

<p><strong>Background:</strong> Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk factors...

Full description

Bibliographic Details
Main Authors: Mojca Globočnik-Petrovič, Andrejka Preskar
Format: Article
Language:English
Published: Slovenian Medical Association 2005-10-01
Series:Zdravniški Vestnik
Subjects:
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/2146
_version_ 1811231881164750848
author Mojca Globočnik-Petrovič
Andrejka Preskar
author_facet Mojca Globočnik-Petrovič
Andrejka Preskar
author_sort Mojca Globočnik-Petrovič
collection DOAJ
description <p><strong>Background:</strong> Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk factors is important for PVR prediction. The distinction between anterior and posterior PVR is essential in predicting the surgery success.</p><p><strong>Conclusions:</strong> The anatomic and first of all functional success after vitrectomy are relatively poor. To improve the outcome the research has been focused on the use of pharmacological agents to prevent the development of PVR. A combination of 5-fluorouracil and low molecular weight heparin is the only proven effective therapy for PVR prevention.</p>
first_indexed 2024-04-12T10:52:19Z
format Article
id doaj.art-b0d24910e45243aab37d66093853cadd
institution Directory Open Access Journal
issn 1318-0347
1581-0224
language English
last_indexed 2024-04-12T10:52:19Z
publishDate 2005-10-01
publisher Slovenian Medical Association
record_format Article
series Zdravniški Vestnik
spelling doaj.art-b0d24910e45243aab37d66093853cadd2022-12-22T03:36:11ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242005-10-0174101640Proliferative vitreoretinopathyMojca Globočnik-PetrovičAndrejka Preskar<p><strong>Background:</strong> Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk factors is important for PVR prediction. The distinction between anterior and posterior PVR is essential in predicting the surgery success.</p><p><strong>Conclusions:</strong> The anatomic and first of all functional success after vitrectomy are relatively poor. To improve the outcome the research has been focused on the use of pharmacological agents to prevent the development of PVR. A combination of 5-fluorouracil and low molecular weight heparin is the only proven effective therapy for PVR prevention.</p>http://vestnik.szd.si/index.php/ZdravVest/article/view/2146proliferative vitreoretinopathyclassificationrisk factorspharmacological therapypars plana vitrectomy
spellingShingle Mojca Globočnik-Petrovič
Andrejka Preskar
Proliferative vitreoretinopathy
Zdravniški Vestnik
proliferative vitreoretinopathy
classification
risk factors
pharmacological therapy
pars plana vitrectomy
title Proliferative vitreoretinopathy
title_full Proliferative vitreoretinopathy
title_fullStr Proliferative vitreoretinopathy
title_full_unstemmed Proliferative vitreoretinopathy
title_short Proliferative vitreoretinopathy
title_sort proliferative vitreoretinopathy
topic proliferative vitreoretinopathy
classification
risk factors
pharmacological therapy
pars plana vitrectomy
url http://vestnik.szd.si/index.php/ZdravVest/article/view/2146
work_keys_str_mv AT mojcaglobocnikpetrovic proliferativevitreoretinopathy
AT andrejkapreskar proliferativevitreoretinopathy