Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles
Substituted thiophene-2-carbaldehydes 1a-dwere utilized in the synthesis of symmetrically substituted thiazolo[5,4-d]thiazoles 3a-d. Bis(5,4-d)thiazoles with thiophene core at the termini are the most employed in the chemistry of materials but exhibit insufficient solubility in majority of organic s...
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SciCell s.r.o.
2018-12-01
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| Series: | Nova Biotechnologica et Chimica |
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| Online Access: | http://www.degruyter.com/view/j/nbec.2018.17.issue-2/nbec-2018-0020/nbec-2018-0020.xml?format=INT |
| _version_ | 1818200108152389632 |
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| author | Tokárová Zita Biathová Anna |
| author_facet | Tokárová Zita Biathová Anna |
| author_sort | Tokárová Zita |
| collection | DOAJ |
| description | Substituted thiophene-2-carbaldehydes 1a-dwere utilized in the synthesis of symmetrically substituted thiazolo[5,4-d]thiazoles 3a-d. Bis(5,4-d)thiazoles with thiophene core at the termini are the most employed in the chemistry of materials but exhibit insufficient solubility in majority of organic solvents with notable impact on the low yields of products. Accordingly, the synthetic approach towards 2,5-dithiophen- 2-yl-thiazolo[5,4-d]thiazole (3a) and its substituted derivatives 3b-d is discussed under the various reaction conditions. Appropriate structural characterisations are included with emphasis on relationship between structure and physicochemical properties highlighting the UV-Vis and fluorescence. |
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| id | doaj.art-b0d3c16bdcb24781b91e1613bf881e2c |
| institution | Directory Open Access Journal |
| issn | 1339-004X |
| language | English |
| last_indexed | 2024-12-12T02:32:25Z |
| publishDate | 2018-12-01 |
| publisher | SciCell s.r.o. |
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| spelling | doaj.art-b0d3c16bdcb24781b91e1613bf881e2c2022-12-22T00:41:22ZengSciCell s.r.o.Nova Biotechnologica et Chimica1339-004X2018-12-0117219320010.2478/nbec-2018-0020nbec-2018-0020Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazolesTokárová Zita0Biathová Anna1Department of Chemistry, Faculty of Natural Sciences, University of SS. Cyril and Methodius in Trnava, Nám. J. Herdu 2,Trnava, SK-917 01, Slovak RepublicDepartment of Chemistry, Faculty of Natural Sciences, University of SS. Cyril and Methodius in Trnava, Nám. J. Herdu 2,Trnava, SK-917 01, Slovak RepublicSubstituted thiophene-2-carbaldehydes 1a-dwere utilized in the synthesis of symmetrically substituted thiazolo[5,4-d]thiazoles 3a-d. Bis(5,4-d)thiazoles with thiophene core at the termini are the most employed in the chemistry of materials but exhibit insufficient solubility in majority of organic solvents with notable impact on the low yields of products. Accordingly, the synthetic approach towards 2,5-dithiophen- 2-yl-thiazolo[5,4-d]thiazole (3a) and its substituted derivatives 3b-d is discussed under the various reaction conditions. Appropriate structural characterisations are included with emphasis on relationship between structure and physicochemical properties highlighting the UV-Vis and fluorescence.http://www.degruyter.com/view/j/nbec.2018.17.issue-2/nbec-2018-0020/nbec-2018-0020.xml?format=INTChemosenzors π-conjugation Dithioxamide Fluorescence Structure-physicochemical properties Thiazolothiazole Thiazolo[5,4-d]thiazole Thiophene-2-carbaldehydes UV-Vis |
| spellingShingle | Tokárová Zita Biathová Anna Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles Nova Biotechnologica et Chimica Chemosenzors π-conjugation Dithioxamide Fluorescence Structure-physicochemical properties Thiazolothiazole Thiazolo[5,4-d]thiazole Thiophene-2-carbaldehydes UV-Vis |
| title | Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles |
| title_full | Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles |
| title_fullStr | Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles |
| title_full_unstemmed | Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles |
| title_short | Synthesis and structure-physicochemical properties relationship of thiophene-substituted bis(5,4-d)thiazoles |
| title_sort | synthesis and structure physicochemical properties relationship of thiophene substituted bis 5 4 d thiazoles |
| topic | Chemosenzors π-conjugation Dithioxamide Fluorescence Structure-physicochemical properties Thiazolothiazole Thiazolo[5,4-d]thiazole Thiophene-2-carbaldehydes UV-Vis |
| url | http://www.degruyter.com/view/j/nbec.2018.17.issue-2/nbec-2018-0020/nbec-2018-0020.xml?format=INT |
| work_keys_str_mv | AT tokarovazita synthesisandstructurephysicochemicalpropertiesrelationshipofthiophenesubstitutedbis54dthiazoles AT biathovaanna synthesisandstructurephysicochemicalpropertiesrelationshipofthiophenesubstitutedbis54dthiazoles |