Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome

Objectives This study aimed to investigate and measure the relationships between the adiponectin levels and oxidized-low density lipoprotein (Ox-LDL) in acute coronary syndrome (ACS) patients in holy Kerbala city, Iraq. Methods Fifty-eight patients included in the study. Patients admitted with a dia...

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Main Authors: Batool Luay Aziz, Ahmed Hussein Al-Mayali, Shaymaa Zahraw Nada, Fatemah Abdullah Mankhi
Format: Article
Language:English
Published: Nab'a Al-Hayat Foundation for Medical Sciences and Health Care - Press 2017-04-01
Series:Journal of Contemporary Medical Sciences
Online Access:http://www.jocms.org/index.php/jcms/article/view/142
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author Batool Luay Aziz
Ahmed Hussein Al-Mayali
Shaymaa Zahraw Nada
Fatemah Abdullah Mankhi
author_facet Batool Luay Aziz
Ahmed Hussein Al-Mayali
Shaymaa Zahraw Nada
Fatemah Abdullah Mankhi
author_sort Batool Luay Aziz
collection DOAJ
description Objectives This study aimed to investigate and measure the relationships between the adiponectin levels and oxidized-low density lipoprotein (Ox-LDL) in acute coronary syndrome (ACS) patients in holy Kerbala city, Iraq. Methods Fifty-eight patients included in the study. Patients admitted with a diagnosis of ACS and 30 control subjects. Circulating adiponectin and Ox-LDL were assessed; using enzyme-linked immunosorbent assays (ELISA). Results Adiponectin serum concentrations were signifcantly lower (p < 0.001) in subjects with ACS compared with control subjects. Ox-LDL serum concentrations were signifcantly higher (p < 0.001) in subjects with ACS compared with controls subjects. The ACS patients showed a signifcantly higher (p < 0.001) result in total cholesterol and signifcantly lower (p < 0.001) level in HDL-C. Conclusion Serum adiponectin negatively correlated with Ox-LDL level in patient group ACS and the healthy control group.
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spelling doaj.art-b0d4e57d2460492e9a1f86792c283b6c2022-12-22T02:15:10ZengNab'a Al-Hayat Foundation for Medical Sciences and Health Care - PressJournal of Contemporary Medical Sciences2415-16292413-05162017-04-0139163166142Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndromeBatool Luay Aziz0Ahmed Hussein Al-Mayali1Shaymaa Zahraw Nada2Fatemah Abdullah Mankhi3Department of Biochemistry, College of Medicine, University of Karbala, Holy Karbala cityDepartment of Biochemistry, College of Medicine, University of Karbala, Holy Karbala cityDepartment of Biochemistry, College of Medicine, University of Karbala, Holy Karbala cityBranch of Immunology Laboratory, in Al-Hussein Teaching Hospital, Al-Hussein Medical City/ Kerbela Health Directorate.Objectives This study aimed to investigate and measure the relationships between the adiponectin levels and oxidized-low density lipoprotein (Ox-LDL) in acute coronary syndrome (ACS) patients in holy Kerbala city, Iraq. Methods Fifty-eight patients included in the study. Patients admitted with a diagnosis of ACS and 30 control subjects. Circulating adiponectin and Ox-LDL were assessed; using enzyme-linked immunosorbent assays (ELISA). Results Adiponectin serum concentrations were signifcantly lower (p < 0.001) in subjects with ACS compared with control subjects. Ox-LDL serum concentrations were signifcantly higher (p < 0.001) in subjects with ACS compared with controls subjects. The ACS patients showed a signifcantly higher (p < 0.001) result in total cholesterol and signifcantly lower (p < 0.001) level in HDL-C. Conclusion Serum adiponectin negatively correlated with Ox-LDL level in patient group ACS and the healthy control group.http://www.jocms.org/index.php/jcms/article/view/142
spellingShingle Batool Luay Aziz
Ahmed Hussein Al-Mayali
Shaymaa Zahraw Nada
Fatemah Abdullah Mankhi
Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
Journal of Contemporary Medical Sciences
title Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
title_full Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
title_fullStr Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
title_full_unstemmed Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
title_short Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome
title_sort impact of adiponectin and oxidized low density lipoprotein in acute coronary syndrome
url http://www.jocms.org/index.php/jcms/article/view/142
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