PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA
Purpose. Prospective study of corneal epithelial layer thickness (CET) changes after the ReLEx® SMILE in case of a low and moderate myopia correction.Material and methods. The «SMILE» study group included 46 patients (46 eyes) with the mean age 26.02±5.18, the mean spherical equivalent was 4.02±0.22...
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| Format: | Article |
| Language: | Russian |
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Publishing house "Ophthalmology"
2017-01-01
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| Series: | Офтальмохирургия |
| Subjects: | |
| Online Access: | https://www.ophthalmosurgery.ru/jour/article/view/296 |
| _version_ | 1828057716707295232 |
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| author | S. N. Sakhnov O. A. Klokova R. O. Damashauskas A. V. Fomin |
| author_facet | S. N. Sakhnov O. A. Klokova R. O. Damashauskas A. V. Fomin |
| author_sort | S. N. Sakhnov |
| collection | DOAJ |
| description | Purpose. Prospective study of corneal epithelial layer thickness (CET) changes after the ReLEx® SMILE in case of a low and moderate myopia correction.Material and methods. The «SMILE» study group included 46 patients (46 eyes) with the mean age 26.02±5.18, the mean spherical equivalent was 4.02±0.22D, the follow-up period was 6 months and less. All patients were examined using the optical coherence tomography (OCT) with the xR AVANTI (Optovue, Inc) pre-operatively and 1 day, 2 weeks, 1, 3, 6 months post-operatively, the ametropia laser correction was performed by the ReLEx® SMILE method using the VisuMax® (500 kHz, Carl Zeiss Meditec AG).Results. After 6 months in 43 patients the uncorrected visual acuity (UCVA) was 0.9-1.0 (93.5%), the refraction within ±0.5D of the planned one was achieved in 89.1% (41 eyes), ±1.0D – in 100% of cases. Epithelial hyperactivity was noted during the first 3 months (Р<0.001). The difference in CET compared with preoperative data in the central corneal area was 5.98±0,38μm (11.09%), the minimum growth was detected in the nasal sector (5-6mm) – 4.19±0.27μm (7.92%), the maximum – in the temporal area (2-5mm sector) – 7.17±0.45μm (13.61%). Epithelial corneal remodeling after the ReLEx® SMILE retained the preoperative statistically significant difference in the CET in the upper and lower segments (Р<0.001) and conversely changed into the opposite pattern in the temporal and nasal segments (Р<0.02).Conclusion. The obtained results show a statistically significant growth of corneal epithelial layer thickness in the correction of low and moderate myopia by the ReLEx® SMILE method predominantly in the early postoperative period. |
| first_indexed | 2024-04-10T21:16:38Z |
| format | Article |
| id | doaj.art-b0da563fd93d40528599e93f53b6fcd2 |
| institution | Directory Open Access Journal |
| issn | 0235-4160 2312-4970 |
| language | Russian |
| last_indexed | 2024-04-10T21:16:38Z |
| publishDate | 2017-01-01 |
| publisher | Publishing house "Ophthalmology" |
| record_format | Article |
| series | Офтальмохирургия |
| spelling | doaj.art-b0da563fd93d40528599e93f53b6fcd22023-01-20T12:34:47ZrusPublishing house "Ophthalmology"Офтальмохирургия0235-41602312-49702017-01-01046168266PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATAS. N. Sakhnov0O. A. Klokova1R. O. Damashauskas2A. V. Fomin3Krasnodar Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionKrasnodar Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionKrasnodar Branch of the S. Fyodorov Eye Microsurgery Federal State InstitutionTradomed Invest CompanyPurpose. Prospective study of corneal epithelial layer thickness (CET) changes after the ReLEx® SMILE in case of a low and moderate myopia correction.Material and methods. The «SMILE» study group included 46 patients (46 eyes) with the mean age 26.02±5.18, the mean spherical equivalent was 4.02±0.22D, the follow-up period was 6 months and less. All patients were examined using the optical coherence tomography (OCT) with the xR AVANTI (Optovue, Inc) pre-operatively and 1 day, 2 weeks, 1, 3, 6 months post-operatively, the ametropia laser correction was performed by the ReLEx® SMILE method using the VisuMax® (500 kHz, Carl Zeiss Meditec AG).Results. After 6 months in 43 patients the uncorrected visual acuity (UCVA) was 0.9-1.0 (93.5%), the refraction within ±0.5D of the planned one was achieved in 89.1% (41 eyes), ±1.0D – in 100% of cases. Epithelial hyperactivity was noted during the first 3 months (Р<0.001). The difference in CET compared with preoperative data in the central corneal area was 5.98±0,38μm (11.09%), the minimum growth was detected in the nasal sector (5-6mm) – 4.19±0.27μm (7.92%), the maximum – in the temporal area (2-5mm sector) – 7.17±0.45μm (13.61%). Epithelial corneal remodeling after the ReLEx® SMILE retained the preoperative statistically significant difference in the CET in the upper and lower segments (Р<0.001) and conversely changed into the opposite pattern in the temporal and nasal segments (Р<0.02).Conclusion. The obtained results show a statistically significant growth of corneal epithelial layer thickness in the correction of low and moderate myopia by the ReLEx® SMILE method predominantly in the early postoperative period.https://www.ophthalmosurgery.ru/jour/article/view/296corneaepitheliummyopiarelex® smile |
| spellingShingle | S. N. Sakhnov O. A. Klokova R. O. Damashauskas A. V. Fomin PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA Офтальмохирургия cornea epithelium myopia relex® smile |
| title | PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA |
| title_full | PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA |
| title_fullStr | PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA |
| title_full_unstemmed | PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA |
| title_short | PECULIARITIES OF CORNEAL EPITHELIAL LAYER STATE AFTER THE RELEX® SMILE ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY DATA |
| title_sort | peculiarities of corneal epithelial layer state after the relex r smile according to optical coherence tomography data |
| topic | cornea epithelium myopia relex® smile |
| url | https://www.ophthalmosurgery.ru/jour/article/view/296 |
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