Trastuzumab deruxtecan for the treatment of patients with HER2-positive gastric cancer
Trastuzumab deruxtecan (T-DXd) is a novel anti-human epidermal growth factor receptor 2 (HER2) antibody–drug conjugate composed of a monoclonal anti-HER2 antibody and a topoisomerase I inhibitor, DX-8951 derivative (an exatecan derivative). T-DXd showed potential anti-tumor activities in HER2-positi...
Main Authors: | Daisuke Kotani, Kohei Shitara |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-01-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758835920986518 |
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