A case of pulmonary tumour thrombotic microangiopathy
Pulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly progressive pulmonary disease that is a fatal complication of malignancy. It manifests clinically as subacute respiratory failure with pulmonary hypertension, progressive right sided heart failure, and sudden death. We describe here a c...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007115000301 |
| _version_ | 1811231557067735040 |
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| author | Shane McAnearney Maire Drain |
| author_facet | Shane McAnearney Maire Drain |
| author_sort | Shane McAnearney |
| collection | DOAJ |
| description | Pulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly progressive pulmonary disease that is a fatal complication of malignancy. It manifests clinically as subacute respiratory failure with pulmonary hypertension, progressive right sided heart failure, and sudden death. We describe here a case of PTTM associated with occult metastatic signet ring cell carcinoma of the stomach. Although rare, PTTM needs to be considered in the differential diagnosis of dyspnoea of unknown origin, particularly in patients with respiratory failure and also pulmonary hypertension, and in patients were there is no improvement in respiratory symptoms with steroid therapy. |
| first_indexed | 2024-04-12T10:46:57Z |
| format | Article |
| id | doaj.art-b0dcbb069c5541c1a41e67c0e0851a54 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-04-12T10:46:57Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-b0dcbb069c5541c1a41e67c0e0851a542022-12-22T03:36:22ZengElsevierRespiratory Medicine Case Reports2213-00712015-01-0116C71010.1016/j.rmcr.2015.04.006A case of pulmonary tumour thrombotic microangiopathyShane McAnearneyMaire DrainPulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly progressive pulmonary disease that is a fatal complication of malignancy. It manifests clinically as subacute respiratory failure with pulmonary hypertension, progressive right sided heart failure, and sudden death. We describe here a case of PTTM associated with occult metastatic signet ring cell carcinoma of the stomach. Although rare, PTTM needs to be considered in the differential diagnosis of dyspnoea of unknown origin, particularly in patients with respiratory failure and also pulmonary hypertension, and in patients were there is no improvement in respiratory symptoms with steroid therapy.http://www.sciencedirect.com/science/article/pii/S2213007115000301Pulmonary tumour thrombotic microangiopathyGastric cancerOncologyInterstitial lung disease |
| spellingShingle | Shane McAnearney Maire Drain A case of pulmonary tumour thrombotic microangiopathy Respiratory Medicine Case Reports Pulmonary tumour thrombotic microangiopathy Gastric cancer Oncology Interstitial lung disease |
| title | A case of pulmonary tumour thrombotic microangiopathy |
| title_full | A case of pulmonary tumour thrombotic microangiopathy |
| title_fullStr | A case of pulmonary tumour thrombotic microangiopathy |
| title_full_unstemmed | A case of pulmonary tumour thrombotic microangiopathy |
| title_short | A case of pulmonary tumour thrombotic microangiopathy |
| title_sort | case of pulmonary tumour thrombotic microangiopathy |
| topic | Pulmonary tumour thrombotic microangiopathy Gastric cancer Oncology Interstitial lung disease |
| url | http://www.sciencedirect.com/science/article/pii/S2213007115000301 |
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