Nanoemulsion Loaded with Clotrimazole Based on Rapeseed Oil for Potential Vaginal Application—Development, Initial Assessment, and Pilot Release Studies

Nanoemulsion Loaded with Clotrimazole Based on Rapeseed Oil for Potential Vaginal Application—Development, Initial Assessment, and Pilot Release Studies

Vaginal candidiasis (VC) is an emerging global hardly treated health issue affecting millions of women worldwide. In this study, the nanoemulsion consisting of clotrimazole (CLT), rapeseed oil, Pluronic F-68, Span 80, PEG 200, and lactic acid was prepared using high-speed and high-pressure homogeniz...

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Bibliographic Details
Main Authors: Michał Smoleński, Susanne Muschert, Dorota Haznar-Garbacz, Katarzyna Małolepsza-Jarmołowska
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
nanoemulsion
clotrimazole
vaginal drug carriers
vaginal candidiasis
EVDF
vaginal drug delivery
Online Access:https://www.mdpi.com/1999-4923/15/5/1437

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