Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice

Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice

BackgroundA feasible method to detect somatic copy number deletion (SCND) of genes is still absent to date.MethodsInterstitial base-resolution deletion/fusion coordinates for CDKN2A were extracted from published articles and our whole genome sequencing (WGS) datasets. The copy number of the CDKN2A g...

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Bibliographic Details
Main Authors: Yuan Tian, Jing Zhou, Juanli Qiao, Zhaojun Liu, Liankun Gu, Baozhen Zhang, Youyong Lu, Rui Xing, Dajun Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
CDKN2A
somatic copy number deletion
common deletion region
multiplex PCR
whole genome sequencing
gastric carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1038380/full

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