Genetic Variation in Angiotensin II Type 1 Receptor Is Linked to Lipid Levels and Hepatic Steatosis in Alcohol-Associated Liver Disease, but Not to Cirrhosis or Hepatocellular Carcinoma

Genetic Variation in Angiotensin II Type 1 Receptor Is Linked to Lipid Levels and Hepatic Steatosis in Alcohol-Associated Liver Disease, but Not to Cirrhosis or Hepatocellular Carcinoma

Background: Development of cirrhosis and hepatocellular carcinoma (HCC) in patients with high alcohol intake is modulated by genetic predispositions. Genetic variation in angiotensin II type 1 receptor (<i>AGTR1</i>) has been described as a risk factor for non-alcoholic fatty liver disea...

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Bibliographic Details
Main Authors: Hans Dieter Nischalke, Franziska Schmalz, Janett Fischer, Christine Möller, Madlen Matz-Soja, Benjamin Krämer, Bettina Langhans, Jacob Nattermann, Thomas Berg, Christian P. Strassburg, Philipp Lutz
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Gastroenterology Insights
Subjects:
cirrhosis
alcohol-associated liver disease
HCC
angiotensin II type 1 receptor
rs3772622
rs2276736
Online Access:https://www.mdpi.com/2036-7422/15/1/2

Internet

https://www.mdpi.com/2036-7422/15/1/2

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