Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i>
The Colorado potato beetle, <i>Leptinotarsa decemlineata</i> Say, is a potato pest that can cause important economic losses to the potato industry worldwide. Diverse strategies have been deployed to target this insect such as biological control, crop rotation, and a variety of insecticid...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Insects |
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| Online Access: | https://www.mdpi.com/2075-4450/14/5/418 |
| _version_ | 1827741166880161792 |
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| author | Kenan Timani Pierre Bastarache Pier Jr Morin |
| author_facet | Kenan Timani Pierre Bastarache Pier Jr Morin |
| author_sort | Kenan Timani |
| collection | DOAJ |
| description | The Colorado potato beetle, <i>Leptinotarsa decemlineata</i> Say, is a potato pest that can cause important economic losses to the potato industry worldwide. Diverse strategies have been deployed to target this insect such as biological control, crop rotation, and a variety of insecticides. Regarding the latter, this pest has demonstrated impressive abilities to develop resistance against the compounds used to regulate its spread. Substantial work has been conducted to better characterize the molecular signatures underlying this resistance, with the overarching objective of leveraging this information for the development of novel approaches, including RNAi-based techniques, to limit the damage associated with this insect. This review first describes the various strategies utilized to control <i>L. decemlineata</i> and highlights different examples of reported cases of resistances against insecticides for this insect. The molecular leads identified as potential players modulating insecticide resistance as well as the growing interest towards the use of RNAi aimed at these leads as part of novel means to control the impact of <i>L. decemlineata</i> are described subsequently. Finally, select advantages and limitations of RNAi are addressed to better assess the potential of this technology in the broader context of insecticide resistance for pest management. |
| first_indexed | 2024-03-11T03:38:51Z |
| format | Article |
| id | doaj.art-b0df38bac8a54c9293239e1ac7c54dc9 |
| institution | Directory Open Access Journal |
| issn | 2075-4450 |
| language | English |
| last_indexed | 2024-03-11T03:38:51Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Insects |
| spelling | doaj.art-b0df38bac8a54c9293239e1ac7c54dc92023-11-18T01:49:36ZengMDPI AGInsects2075-44502023-04-0114541810.3390/insects14050418Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i>Kenan Timani0Pierre Bastarache1Pier Jr Morin2Department of Chemistry and Biochemistry, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, NB E1A 3E9, CanadaDepartment of Chemistry and Biochemistry, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, NB E1A 3E9, CanadaDepartment of Chemistry and Biochemistry, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, NB E1A 3E9, CanadaThe Colorado potato beetle, <i>Leptinotarsa decemlineata</i> Say, is a potato pest that can cause important economic losses to the potato industry worldwide. Diverse strategies have been deployed to target this insect such as biological control, crop rotation, and a variety of insecticides. Regarding the latter, this pest has demonstrated impressive abilities to develop resistance against the compounds used to regulate its spread. Substantial work has been conducted to better characterize the molecular signatures underlying this resistance, with the overarching objective of leveraging this information for the development of novel approaches, including RNAi-based techniques, to limit the damage associated with this insect. This review first describes the various strategies utilized to control <i>L. decemlineata</i> and highlights different examples of reported cases of resistances against insecticides for this insect. The molecular leads identified as potential players modulating insecticide resistance as well as the growing interest towards the use of RNAi aimed at these leads as part of novel means to control the impact of <i>L. decemlineata</i> are described subsequently. Finally, select advantages and limitations of RNAi are addressed to better assess the potential of this technology in the broader context of insecticide resistance for pest management.https://www.mdpi.com/2075-4450/14/5/418Colorado potato beetlecytochrome P450sABC transportersglutathione S-transferasesinsecticide resistancepotato pest |
| spellingShingle | Kenan Timani Pierre Bastarache Pier Jr Morin Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> Insects Colorado potato beetle cytochrome P450s ABC transporters glutathione S-transferases insecticide resistance potato pest |
| title | Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> |
| title_full | Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> |
| title_fullStr | Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> |
| title_full_unstemmed | Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> |
| title_short | Leveraging RNA Interference to Impact Insecticide Resistance in the Colorado Potato Beetle, <i>Leptinotarsa decemlineata</i> |
| title_sort | leveraging rna interference to impact insecticide resistance in the colorado potato beetle i leptinotarsa decemlineata i |
| topic | Colorado potato beetle cytochrome P450s ABC transporters glutathione S-transferases insecticide resistance potato pest |
| url | https://www.mdpi.com/2075-4450/14/5/418 |
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