Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells

Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells

Chinese hamster ovary (CHO) cells are currently the most widely used host cells for recombinant therapeutic protein (RTP) production. Currently, the RTP yields need to increase further to meet the market needs and reduce costs. In this study, three stabilizing and anti-repressor (SAR) elements from...

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Bibliographic Details
Main Authors:	Qin Li, Rui-Fang Yan, Yong-Xiao Yang, Chun-liu Mi, Yan-long Jia, Tian-Yun Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	Chinese hamster ovary cell stabilizing and anti-repressor elements transgene expression epigenetic regulatory elements green fluorescent protein
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.840600/full

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