DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS
The goal of our research was to assess the effect of Enrofloxacin (fluoroquinolone antibacterial drug) on WBC indices of different kinds of poultry at young age. In order to study the dynamics we performed two series of experiments employing groups as follows: Group 1 – control group (one-day-old ch...
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| Format: | Article |
| Language: | English |
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Science and Innovation Center Publishing House
2022-10-01
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| Series: | Siberian Journal of Life Sciences and Agriculture |
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| Online Access: | http://discover-journal.ru/jour/index.php/sjlsa/article/view/610 |
| _version_ | 1797902453076656128 |
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| author | Anna A. Moiseeva Andrey A. Prisnyi Vladimir N. Skvortsov |
| author_facet | Anna A. Moiseeva Andrey A. Prisnyi Vladimir N. Skvortsov |
| author_sort | Anna A. Moiseeva |
| collection | DOAJ |
| description | The goal of our research was to assess the effect of Enrofloxacin (fluoroquinolone antibacterial drug) on WBC indices of different kinds of poultry at young age. In order to study the dynamics we performed two series of experiments employing groups as follows: Group 1 – control group (one-day-old chicks, receiving pure drinking water), Group 2 – experimental group (one-day-old chicks, receiving Enrofloxacin via drinking water at concentration 200 g/L for 10 consecutive days), Groups 3 and 4 were made with one-day-old ducklings, the experiment design was the same as with chicks. Blood samples were drawn from every bird on Day 1, Day 3, Day 5, Day 7 and Day 9 after the drug withdrawal. We performed differential leukocyte count, leukogram was made and we also calculated leukocyte (hematological) indices. The data analysis showed reliable changes of blood indices both in chicks and in ducklings. The greatest changes in the results of both experimental groups as compared to the control groups were observed on Day 7, but they were not lasting. We observed more pronounced and lasting changes in the leukogram of Group 2, while duckling blood showed reliable changes of leukocyte indices. But all in all dynamics in WBC indices that we observed did not show toxic effect of the drug on bird organism. |
| first_indexed | 2024-04-10T09:17:57Z |
| format | Article |
| id | doaj.art-b0e203cf357a48e9a94a5ceba6d0029b |
| institution | Directory Open Access Journal |
| issn | 2658-6649 2658-6657 |
| language | English |
| last_indexed | 2024-04-10T09:17:57Z |
| publishDate | 2022-10-01 |
| publisher | Science and Innovation Center Publishing House |
| record_format | Article |
| series | Siberian Journal of Life Sciences and Agriculture |
| spelling | doaj.art-b0e203cf357a48e9a94a5ceba6d0029b2023-02-20T18:23:23ZengScience and Innovation Center Publishing HouseSiberian Journal of Life Sciences and Agriculture2658-66492658-66572022-10-01145637610.12731/2658-6649-2022-14-5-63-76610DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSISAnna A. Moiseeva0Andrey A. Prisnyi1Vladimir N. Skvortsov2Federal Research Center – All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Ya.R. Kovalenko of the Russian Academy of Sciences, Belgorod DepartmentFederal State Autonomous Educational Institution of Higher Education «Belgorod National Research University»Federal Research Center – All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Ya.R. Kovalenko of the Russian Academy of Sciences, Belgorod DepartmentThe goal of our research was to assess the effect of Enrofloxacin (fluoroquinolone antibacterial drug) on WBC indices of different kinds of poultry at young age. In order to study the dynamics we performed two series of experiments employing groups as follows: Group 1 – control group (one-day-old chicks, receiving pure drinking water), Group 2 – experimental group (one-day-old chicks, receiving Enrofloxacin via drinking water at concentration 200 g/L for 10 consecutive days), Groups 3 and 4 were made with one-day-old ducklings, the experiment design was the same as with chicks. Blood samples were drawn from every bird on Day 1, Day 3, Day 5, Day 7 and Day 9 after the drug withdrawal. We performed differential leukocyte count, leukogram was made and we also calculated leukocyte (hematological) indices. The data analysis showed reliable changes of blood indices both in chicks and in ducklings. The greatest changes in the results of both experimental groups as compared to the control groups were observed on Day 7, but they were not lasting. We observed more pronounced and lasting changes in the leukogram of Group 2, while duckling blood showed reliable changes of leukocyte indices. But all in all dynamics in WBC indices that we observed did not show toxic effect of the drug on bird organism.http://discover-journal.ru/jour/index.php/sjlsa/article/view/610poultryantibacterial drugsfluoroquinolonesenrofloxacinbloodwbc |
| spellingShingle | Anna A. Moiseeva Andrey A. Prisnyi Vladimir N. Skvortsov DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS Siberian Journal of Life Sciences and Agriculture poultry antibacterial drugs fluoroquinolones enrofloxacin blood wbc |
| title | DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS |
| title_full | DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS |
| title_fullStr | DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS |
| title_full_unstemmed | DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS |
| title_short | DYNAMICS OF WBC INDICES IN POULTRY FOLLOWING ENROFLOXACIN ADMINISTRATION: COMPARATIVE ANALYSIS |
| title_sort | dynamics of wbc indices in poultry following enrofloxacin administration comparative analysis |
| topic | poultry antibacterial drugs fluoroquinolones enrofloxacin blood wbc |
| url | http://discover-journal.ru/jour/index.php/sjlsa/article/view/610 |
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