Comprehensive In Silico Analysis of Retrotransposon Insertions within the <i>Survival Motor Neuron</i> Genes Involved in Spinal Muscular Atrophy

Comprehensive In Silico Analysis of Retrotransposon Insertions within the <i>Survival Motor Neuron</i> Genes Involved in Spinal Muscular Atrophy

Transposable elements (TEs) are interspersed repetitive and mobile DNA sequences within the genome. Better tools for evaluating TE-derived sequences have provided insights into the contribution of TEs to human development and disease. Spinal muscular atrophy (SMA) is an autosomal recessive motor neu...

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Bibliographic Details
Main Authors: Albano Pinto, Catarina Cunha, Raquel Chaves, Matthew E. R. Butchbach, Filomena Adega
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biology
Subjects:
spinal muscular atrophy
transposable elements
retrotransposons
genome dynamics
<i>SMN1</i>
<i>SMN2</i>
Online Access:https://www.mdpi.com/2079-7737/11/6/824

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