Increased risk of essential tremor in migraine: A population-based retrospective cohort study.
PURPOSE:To examine the long-term risk of essential tremor (ET) in migraine. METHODS:Using population-based administrative data from a subset of the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 22,696 newly diagnosed migraineurs (mean age 44.5 years) and a matched migr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5348003?pdf=render |
| _version_ | 1811213428073693184 |
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| author | Chi-Ieong Lau Che-Chen Lin Hsuan-Ju Chen Han-Cheng Wang Wei-Hung Chen Ji-An Liang |
| author_facet | Chi-Ieong Lau Che-Chen Lin Hsuan-Ju Chen Han-Cheng Wang Wei-Hung Chen Ji-An Liang |
| author_sort | Chi-Ieong Lau |
| collection | DOAJ |
| description | PURPOSE:To examine the long-term risk of essential tremor (ET) in migraine. METHODS:Using population-based administrative data from a subset of the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 22,696 newly diagnosed migraineurs (mean age 44.5 years) and a matched migraine-free cohort of 90,784 individuals in the period 2000-2008. Multivariable Cox proportional hazards regression analysis was conducted for assessing the ET risk for the migraine cohort compared to the migraine-free cohort. RESULTS:After adjusting for covariates, the migraine cohort had a 1.83-fold increased risk (95% CI 1.50-2.23) of subsequent ET in comparison to the migraine-free cohort (8.97 vs. 4.81 per 10,000 person-years). In the subgroup analysis, patients with migraine were associated with higher risks of ET, regardless of gender, age or the existence of comorbidities. CONCLUSION:Our findings demonstrated an association between migraine and ET, suggesting a possible shared pathophysiology underpinning both disorders. |
| first_indexed | 2024-04-12T05:46:41Z |
| format | Article |
| id | doaj.art-b0e276a2bfde4158b90d12237c8b5040 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T05:46:41Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b0e276a2bfde4158b90d12237c8b50402022-12-22T03:45:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017358610.1371/journal.pone.0173586Increased risk of essential tremor in migraine: A population-based retrospective cohort study.Chi-Ieong LauChe-Chen LinHsuan-Ju ChenHan-Cheng WangWei-Hung ChenJi-An LiangPURPOSE:To examine the long-term risk of essential tremor (ET) in migraine. METHODS:Using population-based administrative data from a subset of the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 22,696 newly diagnosed migraineurs (mean age 44.5 years) and a matched migraine-free cohort of 90,784 individuals in the period 2000-2008. Multivariable Cox proportional hazards regression analysis was conducted for assessing the ET risk for the migraine cohort compared to the migraine-free cohort. RESULTS:After adjusting for covariates, the migraine cohort had a 1.83-fold increased risk (95% CI 1.50-2.23) of subsequent ET in comparison to the migraine-free cohort (8.97 vs. 4.81 per 10,000 person-years). In the subgroup analysis, patients with migraine were associated with higher risks of ET, regardless of gender, age or the existence of comorbidities. CONCLUSION:Our findings demonstrated an association between migraine and ET, suggesting a possible shared pathophysiology underpinning both disorders.http://europepmc.org/articles/PMC5348003?pdf=render |
| spellingShingle | Chi-Ieong Lau Che-Chen Lin Hsuan-Ju Chen Han-Cheng Wang Wei-Hung Chen Ji-An Liang Increased risk of essential tremor in migraine: A population-based retrospective cohort study. PLoS ONE |
| title | Increased risk of essential tremor in migraine: A population-based retrospective cohort study. |
| title_full | Increased risk of essential tremor in migraine: A population-based retrospective cohort study. |
| title_fullStr | Increased risk of essential tremor in migraine: A population-based retrospective cohort study. |
| title_full_unstemmed | Increased risk of essential tremor in migraine: A population-based retrospective cohort study. |
| title_short | Increased risk of essential tremor in migraine: A population-based retrospective cohort study. |
| title_sort | increased risk of essential tremor in migraine a population based retrospective cohort study |
| url | http://europepmc.org/articles/PMC5348003?pdf=render |
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