The visual cortex produces gamma band echo in response to broadband visual flicker.
The aim of this study is to uncover the network dynamics of the human visual cortex by driving it with a broadband random visual flicker. We here applied a broadband flicker (1-720 Hz) while measuring the MEG and then estimated the temporal response function (TRF) between the visual input and the ME...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-06-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1009046 |
| _version_ | 1818579178292772864 |
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| author | Alexander Zhigalov Katharina Duecker Ole Jensen |
| author_facet | Alexander Zhigalov Katharina Duecker Ole Jensen |
| author_sort | Alexander Zhigalov |
| collection | DOAJ |
| description | The aim of this study is to uncover the network dynamics of the human visual cortex by driving it with a broadband random visual flicker. We here applied a broadband flicker (1-720 Hz) while measuring the MEG and then estimated the temporal response function (TRF) between the visual input and the MEG response. This TRF revealed an early response in the 40-60 Hz gamma range as well as in the 8-12 Hz alpha band. While the gamma band response is novel, the latter has been termed the alpha band perceptual echo. The gamma echo preceded the alpha perceptual echo. The dominant frequency of the gamma echo was subject-specific thereby reflecting the individual dynamical properties of the early visual cortex. To understand the neuronal mechanisms generating the gamma echo, we implemented a pyramidal-interneuron gamma (PING) model that produces gamma oscillations in the presence of constant input currents. Applying a broadband input current mimicking the visual stimulation allowed us to estimate TRF between the input current and the population response (akin to the local field potentials). The TRF revealed a gamma echo that was similar to the one we observed in the MEG data. Our results suggest that the visual gamma echo can be explained by the dynamics of the PING model even in the absence of sustained gamma oscillations. |
| first_indexed | 2024-12-16T06:57:34Z |
| format | Article |
| id | doaj.art-b0e49d7f6f73469494359d1aa11dbcb5 |
| institution | Directory Open Access Journal |
| issn | 1553-734X 1553-7358 |
| language | English |
| last_indexed | 2024-12-16T06:57:34Z |
| publishDate | 2021-06-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Computational Biology |
| spelling | doaj.art-b0e49d7f6f73469494359d1aa11dbcb52022-12-21T22:40:15ZengPublic Library of Science (PLoS)PLoS Computational Biology1553-734X1553-73582021-06-01176e100904610.1371/journal.pcbi.1009046The visual cortex produces gamma band echo in response to broadband visual flicker.Alexander ZhigalovKatharina DueckerOle JensenThe aim of this study is to uncover the network dynamics of the human visual cortex by driving it with a broadband random visual flicker. We here applied a broadband flicker (1-720 Hz) while measuring the MEG and then estimated the temporal response function (TRF) between the visual input and the MEG response. This TRF revealed an early response in the 40-60 Hz gamma range as well as in the 8-12 Hz alpha band. While the gamma band response is novel, the latter has been termed the alpha band perceptual echo. The gamma echo preceded the alpha perceptual echo. The dominant frequency of the gamma echo was subject-specific thereby reflecting the individual dynamical properties of the early visual cortex. To understand the neuronal mechanisms generating the gamma echo, we implemented a pyramidal-interneuron gamma (PING) model that produces gamma oscillations in the presence of constant input currents. Applying a broadband input current mimicking the visual stimulation allowed us to estimate TRF between the input current and the population response (akin to the local field potentials). The TRF revealed a gamma echo that was similar to the one we observed in the MEG data. Our results suggest that the visual gamma echo can be explained by the dynamics of the PING model even in the absence of sustained gamma oscillations.https://doi.org/10.1371/journal.pcbi.1009046 |
| spellingShingle | Alexander Zhigalov Katharina Duecker Ole Jensen The visual cortex produces gamma band echo in response to broadband visual flicker. PLoS Computational Biology |
| title | The visual cortex produces gamma band echo in response to broadband visual flicker. |
| title_full | The visual cortex produces gamma band echo in response to broadband visual flicker. |
| title_fullStr | The visual cortex produces gamma band echo in response to broadband visual flicker. |
| title_full_unstemmed | The visual cortex produces gamma band echo in response to broadband visual flicker. |
| title_short | The visual cortex produces gamma band echo in response to broadband visual flicker. |
| title_sort | visual cortex produces gamma band echo in response to broadband visual flicker |
| url | https://doi.org/10.1371/journal.pcbi.1009046 |
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