Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter?
<h4>Background</h4> Galvanic vestibular stimulation (GVS) uses at least one electrode placed on the mastoid process with one or multiple placed over other head areas to stimulate the vestibular system. The exact electrode size used is not given much importance in the literature and has n...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897567/?tool=EBI |
| _version_ | 1811170960987914240 |
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| author | Dennis Q. Truong Alexander Guillen Mujda Nooristani Maxime Maheu Francois Champoux Abhishek Datta |
| author_facet | Dennis Q. Truong Alexander Guillen Mujda Nooristani Maxime Maheu Francois Champoux Abhishek Datta |
| author_sort | Dennis Q. Truong |
| collection | DOAJ |
| description | <h4>Background</h4> Galvanic vestibular stimulation (GVS) uses at least one electrode placed on the mastoid process with one or multiple placed over other head areas to stimulate the vestibular system. The exact electrode size used is not given much importance in the literature and has not been reported in several studies. In a previous study, we compared the clinical effects of using different electrode sizes (3 cm2 and 35 cm2) with placebo but with the same injected current, on postural control. We observed significant improvement using the smaller size electrode but not with the bigger size electrode. The goal of this study was to simulate the current flow patterns with the intent to shed light and potentially explain the experimental outcome. <h4>Methods</h4> We used an ultra-high-resolution structural dataset and developed a model to simulate the application of different electrode sizes. We considered current flow in the brain and in the vestibular labyrinth. <h4>Results</h4> Our simulation results verified the focality increase using smaller electrodes that we postulated as the main reason for our clinical effect. The use of smaller size electrodes in combination with the montage employed also result in higher induced electric field (E-field) in the brain. <h4>Conclusions</h4> Electrode size and related current density is a critical parameter to characterize any GVS administration as the choice impacts the induced E-field. It is evident that the higher induced E-field likely contributed to the clinical outcome reported in our prior study. |
| first_indexed | 2024-04-10T17:05:31Z |
| format | Article |
| id | doaj.art-b0e61f0277764309b078a8edda4545c3 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T17:05:31Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b0e61f0277764309b078a8edda4545c32023-02-06T05:31:01ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01182Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter?Dennis Q. TruongAlexander GuillenMujda NooristaniMaxime MaheuFrancois ChampouxAbhishek Datta<h4>Background</h4> Galvanic vestibular stimulation (GVS) uses at least one electrode placed on the mastoid process with one or multiple placed over other head areas to stimulate the vestibular system. The exact electrode size used is not given much importance in the literature and has not been reported in several studies. In a previous study, we compared the clinical effects of using different electrode sizes (3 cm2 and 35 cm2) with placebo but with the same injected current, on postural control. We observed significant improvement using the smaller size electrode but not with the bigger size electrode. The goal of this study was to simulate the current flow patterns with the intent to shed light and potentially explain the experimental outcome. <h4>Methods</h4> We used an ultra-high-resolution structural dataset and developed a model to simulate the application of different electrode sizes. We considered current flow in the brain and in the vestibular labyrinth. <h4>Results</h4> Our simulation results verified the focality increase using smaller electrodes that we postulated as the main reason for our clinical effect. The use of smaller size electrodes in combination with the montage employed also result in higher induced electric field (E-field) in the brain. <h4>Conclusions</h4> Electrode size and related current density is a critical parameter to characterize any GVS administration as the choice impacts the induced E-field. It is evident that the higher induced E-field likely contributed to the clinical outcome reported in our prior study.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897567/?tool=EBI |
| spellingShingle | Dennis Q. Truong Alexander Guillen Mujda Nooristani Maxime Maheu Francois Champoux Abhishek Datta Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? PLoS ONE |
| title | Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? |
| title_full | Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? |
| title_fullStr | Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? |
| title_full_unstemmed | Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? |
| title_short | Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter? |
| title_sort | impact of galvanic vestibular stimulation electrode current density on brain current flow patterns does electrode size matter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897567/?tool=EBI |
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