Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions
Gold is currently one of the most used metals in organometallic catalysis. The ability of gold to activate unsaturated groups in different modes, together with its tolerance to a wide range of functional groups and reaction conditions, turns gold-based complexes into efficient and highly sought afte...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fchem.2019.00296/full |
| _version_ | 1818172304427843584 |
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| author | Marta Marín-Luna Olalla Nieto Faza Carlos Silva López |
| author_facet | Marta Marín-Luna Olalla Nieto Faza Carlos Silva López |
| author_sort | Marta Marín-Luna |
| collection | DOAJ |
| description | Gold is currently one of the most used metals in organometallic catalysis. The ability of gold to activate unsaturated groups in different modes, together with its tolerance to a wide range of functional groups and reaction conditions, turns gold-based complexes into efficient and highly sought after catalysts. Natural products and relevant compounds with biological and pharmaceutical activity are often characterized by complex molecular structures. (Cyclo)isomerization reactions are often a useful strategy for the generation of this molecular complexity from synthetically accessible reactants. In this review, we collect the most recent contributions in which gold(I)- and/or gold(III)-catalysts mediate intramolecular (cyclo)isomerization transformations of unsaturated species, which commonly feature allene or alkyne motifs, and organize them depending on the substrate and the reaction type. |
| first_indexed | 2024-12-11T19:10:29Z |
| format | Article |
| id | doaj.art-b0e944c91011428bbac8b7b808856bba |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-11T19:10:29Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-b0e944c91011428bbac8b7b808856bba2022-12-22T00:53:48ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462019-05-01710.3389/fchem.2019.00296455526Gold-Catalyzed Homogeneous (Cyclo)Isomerization ReactionsMarta Marín-LunaOlalla Nieto FazaCarlos Silva LópezGold is currently one of the most used metals in organometallic catalysis. The ability of gold to activate unsaturated groups in different modes, together with its tolerance to a wide range of functional groups and reaction conditions, turns gold-based complexes into efficient and highly sought after catalysts. Natural products and relevant compounds with biological and pharmaceutical activity are often characterized by complex molecular structures. (Cyclo)isomerization reactions are often a useful strategy for the generation of this molecular complexity from synthetically accessible reactants. In this review, we collect the most recent contributions in which gold(I)- and/or gold(III)-catalysts mediate intramolecular (cyclo)isomerization transformations of unsaturated species, which commonly feature allene or alkyne motifs, and organize them depending on the substrate and the reaction type.https://www.frontiersin.org/article/10.3389/fchem.2019.00296/fullgoldcatalysisisomerizationallenes1, n-enynes1, n-diynes |
| spellingShingle | Marta Marín-Luna Olalla Nieto Faza Carlos Silva López Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions Frontiers in Chemistry gold catalysis isomerization allenes 1, n-enynes 1, n-diynes |
| title | Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions |
| title_full | Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions |
| title_fullStr | Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions |
| title_full_unstemmed | Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions |
| title_short | Gold-Catalyzed Homogeneous (Cyclo)Isomerization Reactions |
| title_sort | gold catalyzed homogeneous cyclo isomerization reactions |
| topic | gold catalysis isomerization allenes 1, n-enynes 1, n-diynes |
| url | https://www.frontiersin.org/article/10.3389/fchem.2019.00296/full |
| work_keys_str_mv | AT martamarinluna goldcatalyzedhomogeneouscycloisomerizationreactions AT olallanietofaza goldcatalyzedhomogeneouscycloisomerizationreactions AT carlossilvalopez goldcatalyzedhomogeneouscycloisomerizationreactions |