Hereditary thrombotic thrombocytopenic purpura and COVID‐19: Impacts of vaccination and infection in this rare disease

Hereditary thrombotic thrombocytopenic purpura and COVID‐19: Impacts of vaccination and infection in this rare disease

Abstract Introduction Severe COVID‐19 is associated with an important increase of von Willebrand factor and mild lowering of ADAMTS13 activity that may, in the presence of a strong inflammatory reaction, increase the risk of acute thrombotic thrombocytopenic purpura (TTP). Although acute episodes of...

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Main Authors: Erika Tarasco, Anne Sophie vonKrogh, Radomira Hrdlickova, Thomas R. Braschler, Teresa Iwaniec, Paul N. Knöbl, Eriko Hamada, Oleg Pikovsky, Stefan Farese, Odit Gutwein, Petr Kessler, Nina H. Schultz, Charis vonAuer, Jerzy Windyga, Kenneth Friedman, Ingrid Hrachovinova, James N. George, Masanori Matsumoto, Reinhard Schneppenheim, Bernhard Lämmle, Johanna Anna Kremer Hovinga
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
COVID‐19
congenital thrombotic thrombocytopenic purpura (cTTP)
hereditary thrombotic thrombocytopenic purpura (hTTP)
SARS‐CoV‐2
vaccines
Online Access:https://doi.org/10.1002/rth2.12814

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